| 沙眼衣原体生殖道感染动物模型的研究进展 |
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| 引用本文： | 韩燕,尹跃平,钟铭英,郑冰洁. 沙眼衣原体生殖道感染动物模型的研究进展[J]. 中国性病艾滋病防治, 2014, 0(2): 138-140 |
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| 作者姓名： | 韩燕 尹跃平 钟铭英 郑冰洁 |
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| 作者单位： | 中国医学科学院北京协和医学院皮肤病研究所中国疾病控制预防中心性病控制中心,南京210042 |
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| 基金项目： | 国家十二五“重大新药创制”科技重大项目（2012ZX09301002005） |
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| 摘 要： | 沙眼衣原体生殖道感染可以引起性传播疾病，建立沙眼衣原体生殖道感染的动物模型，是了解其致病机制、新药研发及疫苗研制的重要手段。目前主要使用不同型别沙眼衣原体或鼠衣原体模拟沙眼衣原体建立动物模型。用于沙眼衣原体生殖道感染动物模型的动物有：小鼠、灵长类动物、豚鼠、猪等，而小鼠感染动物模型是众多模型中较为经济且易于操作的模型。
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| 关 键 词： | 沙眼衣原体 模型 动物 |
Advances in animal models of Chlamydia trachomatis genital tract infection |
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| Affiliation: | HAN Yan, YIN Yue-ping, ZHONG Ming-ying , et al. (Institute of Dermatology, Chinese Academy of Medical Science and Peking Union Medical College, Nanjing 210042, Jiangsu, China) |
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| Abstract: | C. trachornatis is an important cause of sexually transmitted infection. Establishing animal models of genital C. trachornatis is important to study pathogenesis and develop new drugs and vaccines. Different genotypes of C. trachomatis and mouse pneumonitis are used to inoculate animals. Various animal models have been developed to study genital C. trachomatis infections, including mice, non-human primates, guinea pigs, pigs, and so on. Mouse models are the most economic and easiest to operate among these models. |
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| Keywords: | Chlamydia trachomatis Models Animal |
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