内镜下鼻胆管引流加口服吡喹酮治疗重症华支睾吸虫病

目的 了解十二指肠镜下放置鼻胆管引流加口服吡喹酮治疗重症华支睾吸虫病的疗效。方法 内镜下鼻胆管引流组58例，手术T管引流组26例，两组在年龄、性别、病情等方面有可比性，均于术后8～48h口服吡喹酮驱虫(1．2g／次，每日3次，连服2d)。结果 鼻胆管引流组腹痛、发热、黄疸等症状迅速改善，与手术T管引流组比较，鼻胆管引流症状缓解快、创伤小、术后恢复快、并发症少及治疗费用低。结论 内镜下放置鼻胆管引流加口服吡喹酮治疗重症华支睾吸虫病，是有效、安全的。

Endoscopic nasobiliary drainage and oral praziquantel in treating severe clonorchiasis sinensis

Objective To assess the therapeutic value of endoscopic nasobiliary drainage (ENBD) and oral praziquantel on severe clonorchiasis sinensis. Methods Fifty-eight patients with severe clonorchiasis sinensis were treated by ENBD (observing group, ENBD group) , and other 26 patients treated by surgical operation (control group, operation group). Both groups are matched in age, gender etc. After the procedure all patients receive orally praziquantel 1. 2g, three times a day for 2 days. Results In ENBD group the symptoms, such as abdominal pain, fever, jaundice improved earlier than those in operation group. In compare with the surgical operation, ENBD shares the advantages of earlier remission and recovery, less trauma, scarce complications and low expense. Conclusion ENBD and oral praziquantel is an effective and safe procedure in treating severe clonorchiasis sinensis.