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| 纤维蛋白原与冠心病的相关性 | |
| 引用本文： | 张宜帆,周曼丽,罗晓欣,周霞辉,赵彦禛,俞赟丰,简维雄. 纤维蛋白原与冠心病的相关性[J]. 中国动脉硬化杂志, 2022, 30(5): 431-436 |
| 作者姓名： | 张宜帆 周曼丽 罗晓欣 周霞辉 赵彦禛 俞赟丰 简维雄 |
| 作者单位： | 湖南中医药大学,湖南省长沙市 410208;湖南中医药大学国家重点学科中医诊断学湖南省重点实验室,湖南省长沙市 410208 |
| 基金项目： | 国家自然科学基金项目(81973753)；研究生质量工程项目(2018CX28、2020CX57) |
| 摘 要： | 纤维蛋白原是在肝脏中合成的一种血浆蛋白凝血因子，与凝血功能和炎症反应相关。冠心病是当今社会中高发病率、高死亡率的疾病。已有研究表明血浆纤维蛋白原浓度升高与冠心病的发病、严重程度及预后呈正相关，纤维蛋白原可作为冠心病的独立预测因子。深入研究纤维蛋白原与冠心病的相关性可指导临床诊断与治疗。本文总结了纤维蛋白原与冠心病的相关性研究。 |
| 关 键 词： | 纤维蛋白原 冠心病 动脉粥样硬化 |
| 收稿时间： | 2021-04-28 |
| 修稿时间： | 2021-12-30 |
Correlation between fibrinogen and coronary heart disease |
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| ZHANG Yifan,ZHOU Manli,LUO Xiaoxin,ZHOU Xiahui,ZHAO Yanzhen,YU Yunfeng,JIAN Weixiong. Correlation between fibrinogen and coronary heart disease[J]. Chinese Journal of Arteriosclerosis, 2022, 30(5): 431-436 | |
| Authors: | ZHANG Yifan ZHOU Manli LUO Xiaoxin ZHOU Xiahui ZHAO Yanzhen YU Yunfeng JIAN Weixiong |
| Affiliation: | Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;National Key Discipline of TCM Diagnosis, Hunan Provincial Key Laboratoy, Hunan University of Chinese Mecidine, Changsha, Hunan 410208, China |
| Abstract: | Fibrinogen is a plasma protein coagulation factor synthesized in the liver and is associated with coagulation function and inflammation. Coronary heart disease is a disease with high morbidity and mortality in today''s society. Previous studies have shown that increased plasma fibrinogen concentration is positively correlated with the morbidity, severity and prognosis of coronary heart disease, which can be used as an independent predictor of coronary heart disease. Further study on the correlation between fibrinogen and coronary heart disease can guide clinical diagnosis and treatment. This article reviews the research progress on the correlation between fibrinogen and coronary heart disease. |
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