肝炎后肝硬化患者生存质量调查与影响因素分析

目的测量并评价肝炎后肝硬化患者生存质量（QOL）以及影响因素。方法采用SF-36量表,对220例肝炎后肝硬化患者和220例正常对照者进行QOL测量与评价,并对其影响因素进行单因素分析和多因素逐步回归分析。结果肝炎后肝硬化患者SF-36总评分与对照组相比差异有统计学意义。影响肝炎后肝硬化患者QOL的主要因素是性别、Child-Pugh分级、血小板计数（P=0.004、0.013、0.011）。结论肝炎后肝硬化患者生存质量全面下降,Child-Pugh分级、性别与血小板计数为肝硬化患者生存质量的主要影响因素。

Assessment of Life Quality in Posthepatitis Cirrhosis and Its Influence Factors

Objective To assess the quality of life（QOL）and influence factors of patients with posthepatitis cirrhosis.Methods QOL of 220 patients with posthepatitis cirrhosis and 220 healthy controls were evaluated by Mos SF-36.Single and multiple stepwise regression analysis were made to assess the factors affecting the QOL.Results The average total scores of SF-36 in the posthepatitis cirrhosis group showed significant differences between the posthepatitis cirrhosis group and the control group.The factors affecting the scores of SF-36 were：gender,Child-Pugh grading and blood platelet count（P =0.004,0.013,0.011,respectively）.Conclusions The QOL of patients with posthepatitis cirrhosis declines in general.Gender,Child-Pugh grading and blood platelet count are the most importment influence factors.