The influence of a rapid infusion of glucose on renal dynamics and sodium excretion in patients with arterial hypertension: a preliminary report |
| |
| Authors: | EK J BUCHT H WERKO L |
| |
| Affiliation: | 1. School of Medicine, Faculty of Health Science, Aristotle University of Thessaloniki, Thessaloniki, Greece;2. 1st Paediatric Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Ippokratio General Hospital, Thessaloniki, Greece;1. Data Analytics Research and Evaluation (DARE) Centre, Austin Hospital, University of Melbourne, Melbourne, Australia;2. Australian and New Zealand Intensive Care Research Centre, @ Monash University, Melbourne, Australia;3. Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil;4. Department of Infectious Diseases, Austin Health, Melbourne, Australia;5. Department of Intensive Care, Austin Hospital, Melbourne, Australia;6. Department of Critical Care, University of Melbourne, Melbourne, Australia;7. School of Medicine, University of Melbourne, Melbourne, Australia;8. Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia;9. The Australian Centre for Accelerating Diabetes Innovation, Melbourne Medical School, The University of Melbourne, Melbourne, Australia;10. Department of Endocrinology, Austin Health, Melbourne, Australia;1. Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China;2. Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China;3. Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China;4. Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, China;1. Edinburgh Centre for Endocrinology & Diabetes, Royal Infirmary of Edinburgh, Edinburgh, UK;2. University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK;3. Edinburgh Centre for Endocrinology & Diabetes, Western General Hospital, Edinburgh, UK;4. Edinburgh Centre for Endocrinology & Diabetes, St John''s Hospital, Edinburgh, UK;1. Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America;2. DPP/DPPOS Coordinating Center, Biostatistics Center, The George Washington University, Rockville, MD, United States of America;3. Tufts Medical Center, Boston, MA, United States of America;4. Albert Einstein College of Medicine, Bronx, NY, United States of America;5. Colorado School of Public Health, University of Colorado, Denver, CO, United States of America;6. Schools of Medicine and Public Health, University of Michigan, Ann Arbor, MI, United States of America;7. DPP/DPPOS Coordinating Center, Biostatistics Center (Consultant), The George Washington University, Rockville, MD, United States of America;8. University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, United States of America;9. Division of Endocrinology, Parkview Health, Fort Wayne, IN, United States of America;10. David Geffen School of Medicine at UCLA, Los Angeles, CA, United States of America;11. Washington University School of Medicine, St. Louis, MO, United States of America;12. Massachusetts General Hospital Diabetes Center, Harvard Medical School, Boston, MA, United States of America |
| |
| Abstract: | ![]()
- 1.1. The renal clearances for inulin, endogenous creatinine, sodium paraaminohippurate and sodium excretion were determined in nine cases of arterial hypertension before and during a rapid infusion of 5 or 3 per cent glucose in water.
- 2.2. The low basal clearances immediately increased to normal or near normal values in all cases when the rapid infusion was started.
- 3.3. The excretion of sodium and water slowly increased during the experiment. The diuresis increased approximately to a rate about 50 per cent of the infusion rate. The sodium excretion increased up to several hundred per cent. There was a statistically significant negative correlation between the basal value for sodium excretion and the maximal value reached during the infusion.
- 4.4. The glomerular filtration rate and sodium excretion varied independently of each other.
- 5.5. In four cases where the blood pressure was followed during and after the study, it decreased markedly for several days.
|
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
