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吉西他滨联合卡铂治疗复发性上皮性卵巢癌临床分析
引用本文:刘玉娟,周洪贵,谌伦华,李佳平,蒋静. 吉西他滨联合卡铂治疗复发性上皮性卵巢癌临床分析[J]. 中国误诊学杂志, 2011, 11(35): 8575-8576
作者姓名:刘玉娟  周洪贵  谌伦华  李佳平  蒋静
作者单位:川北医学院附属医院,四川南充,637000
摘    要:
目的 探讨吉西他滨(Gem)联合卡铂治疗复发性上皮性卵巢癌的有效性和不良反应.方法 采用随机对照研究的方法,将2008-08-2010-12间在川北医学院附属医院收治的48例复发性上皮性卵巢癌患者随机分为研究组(Gem联合卡铂)和对照组(紫杉醇联合卡铂),对其疗效及不良反应进行比较.结果 对照组和研究组完全缓解率(CR)分别为12.5%和29.17%,总有效率分别为45.83%和79.17%,不良反应分别提高54.17%和25.00%.研究组CR和总有效率明显高于对照组(P<0.01),研究组治疗后不良反应明显低于对照组(P<0.01).结论 Gem联合卡铂治疗复发性上皮性卵巢癌的临床疗效较好,不良反应较低.

关 键 词:卵巢肿瘤/药物疗法  脱氧胞苷/类似物和衍生物/治疗应用  卡铂/治疗应用  治疗结果  人类

Clinical analysis of Gemcitabine and Carboplatin in treatment of recurrent epithelial ovarian cancer
LIU Yu-juan,ZHOU Hong-gui,CHEN Lun-hua,LI Jia-ping,HANG Jing. Clinical analysis of Gemcitabine and Carboplatin in treatment of recurrent epithelial ovarian cancer[J]. Chinese Journal of Misdiagnostics, 2011, 11(35): 8575-8576
Authors:LIU Yu-juan  ZHOU Hong-gui  CHEN Lun-hua  LI Jia-ping  HANG Jing
Affiliation:LIU Yu-juan,ZHOU Hong-gui,CHEN Lun-hua,LI Jia-ping,JIANG Jing Department of Obstetrics and Gynecology,The Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China
Abstract:
Objective To investigate the therapeutic effects and adverse effects of Gemeitabine and Carboplatin in treatment of recurrent epithelial ovarian cancer.Methods The controlled study for the randomized cases was performed in 48 patients with recurrent epithelial ovarian cancer in our department between Aug 2008 and Dec 2010.The patients were divided randomly into study group(24 cases) and control group(24 ases).Study group received the treatment of Gemeitabine and Carboplatin.Control group received the treatm...
Keywords:Ovarian Neoplasms/drug therapy  Deoxycytidine/analogs & derivatives/therapeutic use  Carboplatin/drugtherapy  Female  Treatment Outcome  
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