微量泵注入胰岛素在糖尿病酮症酸中毒抢救中的应用

目的观察微量注射泵胰岛素输注在糖尿病酮症酸中毒抢救中的疗效。方法将193例糖尿病酮症酸中毒患者随机分成研究组和对照组,研究组102例,对照组91例。研究组用微量注射泵持续静脉推注胰岛素,对照组持续静脉滴注胰岛素,观察两组血糖下降速度及血酮消除的速度,以及出现低血糖的风险等。结果与对照组比较,研究组血糖下降更平稳;血酮体阴转时间[(26.25±17.92)h vs.(30.82±18.27)h]、低血糖发生人次[(1.20±2.02)人次vs.(1.93±3.16)人次]及平均住院日[(9.19±4.07)d vs.(11.37±5.77)d]明显降低(P<0.05)。结论微量泵胰岛素输注在糖尿病酮症酸中毒中的抢救效果优于传统的小剂量胰岛素持续静脉滴。

Application of micropump insulin injection in the treatment of diabetic ketoacidosis

Objective To observe the effect of micropump insulin injection in the treatment of diabetic ketoacidosis.Methods 193 diabetic ketoacidosis patients were randomly divided into experimental group and control group.102 patients were given insulin with micropump injection in experimental group,and 91 patients were given insulin by intravenous drop infusion in control group.Results Compared to the control group,the level of blood glucose decreased move steadily,the elimination of blood acetone body was faster,the rate of Hypoglycemia was lower in the experimental group（P0.05）.Conclusion Insulin given with micropump injection is a safe method with stable decrease of blood glucose and faster elimination of blood acetone body,which is superior to the traditional intravenous infusion method.