Changes and bioactivities on volatile organic compounds of endophytic fungi Neurospora dictyophora 3ZF-02 in different ages |
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| Authors: | Hui Zhang Lin Xu Xiaohui Kong Xiaokang Ji Shengli Yang |
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| Affiliation: | 1. School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China;2. The Center for TCM Standardization, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China;3. The College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China |
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| Abstract: | The endophytic fungus Neurospora dictyophora 3ZF-02 with a special aroma was isolated from the arils of Torreya grandis. Analysis of volatile organic compounds was done by gas chromatography–mass spectrometry. A total of 46 compounds were identified in the volatile organic compounds by 3ZF-02. In the growth phase, esters, acids, along with some alcohols and ketones were the main components. During the recession period, a large amount of benzene and naphthalene compounds appeared, accompanied by the production of amines. Oleic acid, methyl abietate, terpinen-4-ol were also found. They were the same ingredients in essential oil of Torreya. The antioxidant activity and antifungal activity of all extracts were also evaluated. When cultured for 10 days, it exhibited the most significant antioxidant activity with IC50 of 1.44 and 0.95 g/L against diphenyl picryl hydrazinyl and hydroxyl radicals, respectively. In addition, the extracts cultured for 10 days exhibited the most significant antifungal activity against Candida albicans with minimum inhibitory concentration 1.56 mg/ml. |
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| Keywords: | antifungal activity antioxidant activity gas chromatography–mass spectrometry Neurospora dictyophora volatile organic compounds |
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