| 低分子肝素抗凝治疗延长肿瘤患者生存机制的研究进展 |
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| 引用本文： | 褚彬,白砚霞.低分子肝素抗凝治疗延长肿瘤患者生存机制的研究进展[J].临床肿瘤学杂志,2011,16(12):1142-1145. |
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| 作者姓名： | 褚彬 白砚霞 |
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| 作者单位： | １０００３５ 北京 北京积水潭医院血液内科 |
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| 摘 要： | 肿瘤患者凝血系统常被激活而处于高凝状态,易于形成血栓.静脉血栓事件的防治是目前肿瘤研究中的热点.近年来有研究表明低分子肝素在治疗肿瘤患者深静脉血栓形成的同时能延长患者的生存.本文简要综述有关低分子肝素抗凝治疗延长肿瘤患者生存及其分子机制的研究进展.
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| 关 键 词： | 低分子肝素 深静脉血栓形成 血管新生 增殖 凋亡 |
| 收稿时间： | 2011-02-28 |
| 修稿时间： | 2011-06-06 |
The molecular mechanism of low-molecular-weight heparin improving the survival of cancer patients |
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| CHU Bin
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BAI Yan-xia.The molecular mechanism of low-molecular-weight heparin improving the survival of cancer patients[J].Chinese Clinical Oncology,2011,16(12):1142-1145. |
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| Authors: | CHU Bin BAI Yan-xia |
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| Institution: | CHU Bin,BAI Yan-xia. Department of Hematology,Beijing Jishuitan Hospital,Beijing 100035,China |
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| Abstract: | The blood coagulation system is always activated in cancer patients and hypercoagulative state tends to cause thrombosis.Recent studies has showed that low molecular weight heparin for the initial treatment of deep vein thrombosis can improve the survival of cancer patients.In this review we briefly summarize the advance of low molecular weight heparin treatment on survival of cancer patients and the molecular mechanism involved. |
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| Keywords: | Low-molecular-weight heparin Deep vein thrombosis Angiogenesis Proliferation Apoptosis |
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