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Detection and identification of occult HBV in blood donors in Taiwan using a commercial,multiplex, multi‐dye nucleic acid amplification technology screening test
Authors:K. T. Lin  C. L. Chang  M. H. Tsai  K. S. Lin  J. Saldanha  C. M. Hung
Affiliation:1. Kaohsiung Blood Center, Taiwan Blood Services Foundation, , Kaohsiung, Taiwan;2. Roche Diagnostics, Ltd., , Taipei, Taiwan;3. Taiwan Blood Services Foundation, , Zhongzheng, Taipei City, Taiwan;4. Roche Molecular Systems, , Pleasanton, CA, USA
Abstract:
Platelet components became routinely available to many institutions in the late 1960s and since then utilization has steadily increased. Platelets are produced by three principal methods and their manufacturing process is regulated by multiple agencies. As the field of platelet transfusion has evolved, a broad array of strategies to improve platelet safety has developed. This review will explore the evolution of modern platelet component therapy, highlight the various risks associated with platelet transfusion and describe risk reduction strategies that have been implemented to improve platelet transfusion safety. In closing, the reader will be briefly introduced to select investigational platelet and platelet‐mimetic products that have the potential to enhance platelet transfusion safety in the near future.
Keywords:blood screening  multi‐dye  NAT test  occult HBV
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