小柴胡汤联合认知行为疗法对躯体形式障碍的疗效相关因素分析

目的 探讨影响小柴胡汤联合心理干预对躯体形式障碍（somatoform disorders，SFD）患者的疗效相关因素。方法 采用单盲抽样法，选取广西中医药大学第一附属医院脑病科门诊及住院部的SFD患者为研究对象，将SFD患者的年龄、依从性、躯体形式障碍程度、疗程、心理干预频率、病程、职业、中医证型、治疗方式等资料进行赋值，采用Logistic回归分析法进行相关因素分析。结果 单因素分析表明，SFD患者的年龄、依从性、病程、躯体形式障碍严重程度、疗程、心理干预频率、中医证型、治疗方式与疗效存在相关性 （P<0.05）；Logistic回归分析显示，躯体障碍程度是影响小柴胡汤联合认知行为疗法治疗SFD患者疗效的最大因素（OR=5.675，P<0.05）。结论 小柴胡汤联合认知行为疗法治疗躯体形式障碍有效，同时应关注影响疗效的相关因素，有助于提高疗效。

Clinical Effect of Xiaochaihu Decoction Combined with Cognitive Behavioral Therapy on Somatoform Disorders and Related Factors

Objective To investigate the influencing factors for the clinical effect of Xiaochaihu Decoction combined with psychological intervention in patients with somatoform disorders (SFD). Methods The single-blind sampling method was used to select the patients with SFD who were treated in the outpatient service and inpatient department of The First Affiliated Hospital of Guangxi University of Chinese Medicine. Values were assigned for the data including age, compliance, SFD severity, course of treatment, frequency of psychological intervention, course of the disease, occupation, traditional Chinese medicine (TCM) syndrome type, and treatment modality, and a logistic regression analysis was used to investigate related factors. Results The univariate analysis showed that age, compliance, course of the disease, SFD severity, course of treatment, frequency of psychological intervention, TCM syndrome type, and treatment modality were associated with clinical outcome in the patients with SFD (P<0.05), and the logistic regression analysis showed that SFD severity was the most important influencing factor for the clinical effect of Xiaochaihu Decoction combined with cognitive behavioral therapy in the patients with SFD (odds ratio = 5.675, P<0.05). Conclusion Xiaochaihu Decoction combined with cognitive behavioral therapy is an effective method for the treatment of SFD, and related influencing factors should be taken seriously to improve the clinical effect of this treatment.