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Two new norbisabolane sesquiterpenoid glycosides from Glochidion coccineum
Authors:HAI-TAO Xiao   HONG-PING He   JIAO Peng   YUE-HU Wang   XIAN-WEN Yang   XU-JIA Hu   XIAO-YAN Hao   XIAO-JIANG Hao
Affiliation: a School of Pharmacy, Guiyang Medical University, Guiyang, Guizhou, Chinab The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, Chinac Department of Pharmacology, Guiyang Medical University, Guiyang, Guizhou, Chinad School of Pharmacy, Second Military Medical University, Shanghai, China
Abstract:
Two new norbisabolane sesquiterpenoid glycosides, glochicoccinosides A (1) and B (2), together with two known compounds, have been isolated from the rhizomes of Glochidion coccineum. Their structures were elucidated by the combination of 1D NMR, 2D NMR, and MS spectral analysis, as well as chemical evidence. Cytotoxic activities and the antioxidant effect of these compounds were evaluated, but none of them showed activity.
Keywords:Euphorbiaceae  Glochidion coccineum  Norbisabolane sesquiterpenoid glycosides  Glochicoccinoside A  Glochicoccinoside B
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