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Basaloid squamous carcinoma of the oral cavity: Report of a case
Affiliation:1. Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India;2. Department of Pathology, Jagadguru Jayadeva Murugarajendra Medical College, Davanagere, India;3. Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India;4. Department of Oral and Maxillofacial Pathology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences, MSR Nagar, Bengaluru-560054 Karnataka, India;5. Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral and Maxillofacial Surgery, College of Dentistry, Jazan University, Saudi Arabia;6. College of Dental Medicine, Roseman University of Health Sciences, South Jordan, Utah, United States;7. Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Saudi Arabia
Abstract:
A case of basaloid squamous carcinoma that involves the posterior buccal mucosa is described. The major histopathologic feature is a carcinoma with a basaloid pattern in association with squamous differentiation. The basaloid cells exhibit large and vesicular nuclei and eosinophilic clear or vacuolated cytoplasm. Cells are distributed in cords, trabeculae, or lobules that occasionally show glandular arrangement. The majority of the tumor cells are positive for keratin and a large group of cells distributed in glandular arrangement are positive also for vimentin.
Keywords:
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