缺血性中风患者急性期DWI影像ADC值与中医证候的关系探讨

目的:通过观察缺血性中风患者急性期扩散加权成像(DWI)ADC值的变化,对照其中医证候变化,探究二者的相关性。方法:选择符合纳入标准的缺血性中风急性期患者60例,按中医证候标准分为风、火热、痰、瘀、气虚、阴虚阳亢六大证候,观察发病6～48 h及10 d时的证候变化。同时分别于发病6～48 h及10 d时检查ADC值,并与证候值的变化比较,进行统计学处理。结果:各证候的ADC值在发病6～48 h内组间比较差异无统计学意义;发病10 d时均明显升高,与发病6～48 h比较差异有统计学意义(P<0.05),组间比较风证和火热证的ADC值升高明显,较其他证候差异有统计学意义(P<0.05)。结论:中医证候的演变与ADC值有相关性,并且风证和火热证的ADC值变化较其他证候差异有统计学意义,可把ADC值升高明显者作为风证、火热证辨证的客观参考指标之一。因此,DWI影像ADC值的变化可以作为中医证候诊断的客观辅助指标和手段。

The correlation research between the ADC value of DWI and evolution regularity of chinese traditional medicine syndrome in ischemic stroke patients during the acute period

Objective： To investigate the mobile changes of Chinese medicine syndrome in ischemie stroke patients during the acute period, observe changes of ADC value about DWI imaging, research the correlation between them. Methods： 60 cases of diagnosed with acute ischemic stroke according with the criterion of diagnosis were randomly choosed, which were divided into six syndromes, obtain the ADC value within 48 hours and after 10 days, which were compared with the Chinese medicine syndrome value above. All data was processed using the statistics software. Results： the ADC value of each syndrome was all at low level in the beginning, which had no significant difference. Great changes of ADC value had taken place at the tenth day, ADC values of feng and huore syndromes upgraded apparently, which had significant difference comparing with the other syndromes（ P 〈0.05）. Conclusion： The research indicates that there is the correlation relationship between mobile evolution of Chinese medicine syndrome and the changes of ADC value in ischemic stroke patients during the acute period. The changes of ADC values in feng and huore syndromes have significant difference comparing with the other syndromes. The up growth of ADC value may be as one of the objective standards when feng and huore syndromes are diffreentiated. So changes of ADC value about DWI imaging may be as the objective supplementary means and index during the course of differentiating Chinese medicine syndrome.