洛赛克胶囊联合阿莫西林胶囊、甲硝唑片治疗消化性溃疡并幽门螺杆菌感染的疗效

目的观察洛赛克胶囊联合阿莫西林胶囊、甲硝唑片治疗消化性溃疡并幽门螺杆菌感染的临床疗效。方法48例消化性溃疡并幽门螺杆菌感染病人（其中胃溃疡15例,十二指肠溃疡33例）,均给予洛赛克胶囊20 mg口服,2次/d;阿莫西林胶囊1.0 g口服,2次/d;甲硝唑片0.4 g口服,2次/d。疗程为7 d。48例病人疗程结束后4周复查胃镜,并检测幽门螺杆菌。结果48例病人中,愈合率为91.7%（44/48）,有效率为96.4%（46/48）,幽门螺杆菌根除率为87.2%（42/48）。结论洛赛克胶囊联合阿莫西林胶囊、甲硝唑片是治疗消化性溃疡并幽门螺杆菌感染的理想药物。

Curative Effect of Peptic Ulcer and Helicobacter Pylori Infection in Treatment with Losec Capsule Combined with Amoxicillin Capsules and Metronidazole Tablets

Objective To observe the clinical curative effect of combined administration of Losec capsule, Amoxicillin capsules and Metronidazole tablets on peptic ulcer and Helicobacter pylori infection. Methods forty-eight peptic ulcer cases with Helicobacter pylori infection,including 15 cases of gastric ulcer and 33 of duodenal ulcer,were treated for 7 days with losec capsules （20 mg orally taken twice/d）, amoxicillin capsules （1.0 g orally taken twice/d）, and metronidazole tablets （0. 4 g orally taken twice/d）. At 4 weeks after the treatment, the patients underwent gastroscopy and detection of Helicobacter pylori. Results For the 48 patients, the healing rate was 91.7% （44/48） ,effectiveness rate was 96.4% （46/48）, Helicobacter pylori eradication rate was 87.2% （42/48）. Conclusion The combined administration of Losec capsule, Amoxicillin capsules and Metronidazole tablets may be an ideal therapy for peptic ulcer and Helicobacter pylori infection.