| 脂质过氧化作用对培养心肌细胞维生素E含量及膜流动性的影响 |
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| 引用本文： | 王光武 赵轶卓. 脂质过氧化作用对培养心肌细胞维生素E含量及膜流动性的影响[J]. 营养学报, 1996, 18(1): 35-38 |
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| 作者姓名： | 王光武 赵轶卓 |
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| 作者单位： | 白求恩医科大学地方病研究所，中国医学科学院心血管病研究所 |
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| 摘 要： | 应用氢过氧化枯烯引发培养乳鼠的心肌细胞脂质过氧化损伤，观察维生素Ｅ含量及细胞膜流动性的变化。结果显示：脂质过氧化作用能引起心肌细胞维生素Ｅ含量明显下降，其中以ｒ一生育酚的消耗更为显著，细胞膜流动性也降低。提示维生素Ｅ在对抗心肌细胞脂质过氧化损伤上起重要作用。
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| 关 键 词： | 维生素E，膜流动性，脂质过氧化，心肌细胞 |
EFFECT OF CUMENE HYDROPEROXIDE INDUCED CHANGES ON VITAMIN ECONTENT AND MEMBRANE FLUIDITY OF CULTURED NEONATAL RAT HEART CELLS |
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| Wang Guangwu,Zhao Yizhuo,Wang Fan, Li Tiyuan. EFFECT OF CUMENE HYDROPEROXIDE INDUCED CHANGES ON VITAMIN ECONTENT AND MEMBRANE FLUIDITY OF CULTURED NEONATAL RAT HEART CELLS[J]. Acta Nutrimenta Sinica, 1996, 18(1): 35-38 |
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| Authors: | Wang Guangwu Zhao Yizhuo Wang Fan Li Tiyuan |
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| Abstract: | he changes of vitdmin E content and cell membrane fluidity induced by cumene hydroperoxide in cultured neonatal rat heart cells was investi一gated,The results showed that cumene hydroperoxide caused an obvious decreanse of vitamin E content and cell membrane fluidity and increase of the concentration of lipid peroxide, These indicated that vitamin E might play an important role against the lipid peroxidation induced by cumene hydroperoxide. |
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| Keywords: | vitamin E membrane fluidity lipid peroxidation beart cell |
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