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Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients
Authors:Gan Muneuchi  Shigehiko Suzuki  Masayuki Onodera  Osamu Ito  Yuiro Hata  Hiroharu H. Igawa
Affiliation:1. Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Kagawa University, Kagawamuneuchi@med.kagawa-u.ac.jp;3. Department of Plastic and Reconstructive Surgery, Kyoto University Graduate School of Medicine, Kyoto;4. Department of Pathology and Host Defense, Faculty of Medicine, Kagawa University, Kagawa;5. Department of Plastic and Reconstructive Surgery, Kagawa Prefectural Central Hospital, Kagawa;6. Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Tokyo Medical and Dental University, Tokyo, Japan;7. Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Kagawa University, Kagawa
Abstract:
We studied the long-term outcome of injection of triamcinolone acetonide into keloid scars in Asian patients. Between 1985 and 2003, we treated 109 keloid scars in 94 patients by injecting 1 to 10?mg of triamcinolone acetonide depending on the size of the lesion at four week intervals. There was little morbidity. Thirty-one patients gave up treatment within 10 injections because of pain and lack of immediate improvement. Improvement in subjective symptoms was seen in 52 of the remaining 63 patients (82%). In objective symptoms, fair or better results were seen in 40 of 63 (63%), and good or better results in 25 of 63 (39%). The treatment method required 20–30 injections over three to five years. Although we did not achieve as good results as other authors, we think it was safer because we used a smaller dose of a steroid.
Keywords:keloid  triamcinolone acetonide  intralesional injection  Asian  Kagawa University Scale
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