国人颈动脉内膜-中膜厚度与心血管疾病的相关性研究

目的：探讨颈动脉内膜－中膜厚度（IMT）在心血管疾病中的意义。方法：对一组男性心血管疾病易患人群（358例）进行常规体检，包括心血管疾病及其危险因素的调查；同时应用血管超声技术测量双侧颈总动脉、分叉处及颈内动脉后壁IMT。采用相关分析及多元线性回归方程分析颈动脉IMT与心血管疾病及其危险因素之间的关系。结果：颈动脉IMT与年龄、血压及血糖呈正相关，与开始吸烟年龄呈负相关。进一步研究表明高血压病、糖尿病及心肌梗塞、脑卒中患者的IMT值显著高于其各自对照组（P＜0．05），而心绞痛患者颈动脉IMT值虽然高于对照组，但差异无显著性意义（P＞0．05）。结论：超声检测颈动脉IMT可作为监测心血管疾病发生及发展的一项有意义的指标。

Correlation of Carotid Arterial Intima-media Thickness with Cardiovascular Disease Assessed by Ultrasound

Objective:To study the correlation of carotid arterial intima-media thickness (IMT) with cardiovascular disease assessed by ultrasound.Methods:Three hundred and fifty eight male subjects aged 55 to 74 years were investigated for cardiovascular risk factors Their blood pressure , glucose, total cholesterol and triglycerides were measured Meantime the maximum IMT of the far wall for 1 cm lengths of the distal common carotid,carotid bifurcation and the proximal internal carotid,bath of right and left were measured by ultrasound.Results:The mean IMT was correlated with age, blood pressure, glucose and cigarette pack-years Further research demonstrated that IMT of the patients with hypertension, diabetes mellitus, myocardial infarction and stroke was much higher than that of their own control groups( P <0 05), especially for the patients with hypertension( P <0 01).IMT of the patients with angina was higher than that of the control group, which did not have statistically significance( P >0 05).Conclusions:IMT in Carotid artery measured by ultrasound is a significant indicator in the clinical course of cardiovascular disease.