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Stress-activated protein kinase inhibition to ameliorate lung ischemia reperfusion injury
Authors:Wolf Patrick S  Merry Heather E  Farivar Alexander S  McCourtie Anton S  Mulligan Michael S
Affiliation:Division of Thoracic Surgery, University of Washington, Seattle, Wash
Abstract:
Keywords:AM, alveolar macrophage   AP-1, activator protein 1   BSA, bovine serum albumin   CINC, cytokine-induced neutrophil chemoattractant   DMSO, dimethylsulfoxide   ERK1/2, extracellular signal-regulated kinase   IL-1β, interleukin 1β   JNK, c-jun N-terminal kinase   LIRI, lung ischemia-reperfusion injury   MAPK, mitogen-activated protein kinase   MPO, myeloperoxidase   NF-κB, nuclear factor κB   PBS, phosphate-buffered saline solution   SAPK, stress-activated protein kinase
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