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制霉素软膏中制霉素含量测定方法的研究
引用本文:周修森. 制霉素软膏中制霉素含量测定方法的研究[J]. 中国医药导报, 2011, 8(11): 52-53
作者姓名:周修森
作者单位:河南省信阳市食品药品检验所,河南信阳,464000
摘    要:
目的:建立制霉素软膏中制霉素含量测定的方法。方法:采用紫外-可见分光光度法测定制霉素软膏中制霉素的含量,检测波长为319 nm。结果:制霉素浓度在36.06~84.15 U/ml范围内与吸光度呈良好的线性关系(r=0.999 6),平均回收率为100.4%,RSD为0.6%。结论:所建立的方法简便、快捷,测量结果准确,适用于该制剂的含量测定。

关 键 词:制霉素软膏  紫外一可见分光光度法  含量测定

Study on the content determination of nystatini in Nystatini Ointment
ZHOU Xiusen. Study on the content determination of nystatini in Nystatini Ointment[J]. China Medical Herald, 2011, 8(11): 52-53
Authors:ZHOU Xiusen
Affiliation:ZHOU Xiusen Xinyang Institute for Food and Drug Control,Xinyang 464000,China
Abstract:
Objective: To establish a simple and sensitive method for determination of nystatini in Nystatini Ointment.Methods: UV-Vis Spectrophotometry was used to determine nystatini in Nystatini Ointment,the detective wavelength was 319 nm.Results: A good linearity was obtained over the range of 36.06-84.15 U/ml(r=0.999 6) for nystatini.The average recovery was 100.4%,and the RSD was 0.6%.Conclusion: The method is simple,rapid and accurate for quantitative analysis.
Keywords:Nystatini Ointment  UV-Vis Spectrophotometry  Content determination  
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