银杏叶提取物对小鼠免疫功能的影响 |
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引用本文: | 熊平源,胡艺兰,陈慧,王强,白惠卿. 银杏叶提取物对小鼠免疫功能的影响[J]. 数理医药学杂志, 2012, 0(6): 724-725 |
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作者姓名: | 熊平源 胡艺兰 陈慧 王强 白惠卿 |
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作者单位: | [1]武汉科技大学医学院,武汉430065 [2]北京大学医学部,武汉430065 |
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摘 要: | 目的:了解银杏叶提取物对小鼠免疫功能的影响。方法:采用体外抗体形成细胞检测法检测银杏叶提取物对小鼠脾细胞产生抗体的影响;采用间接免疫荧光法测定银杏叶提取物对小鼠CD4+/CD8+T淋巴细胞亚群的影响;采用3 H-TdR掺入法检测银杏叶提取物对小鼠淋巴细胞转化活性的影响。结果:银杏叶提取物有促进小鼠体液免疫功能的作用(P<0.01);能通过调整CD4+/CD8+T细胞亚群的比值来增强小鼠免疫功能(P<0.05);能增加小鼠淋巴细胞转化活性(P<0.001)。结论:银杏叶提取物能增强小鼠免疫功能。
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关 键 词: | 银杏叶 抗体形成细胞 淋巴细胞转化 T淋巴细胞亚群 |
Ginkgo Biloba Extract on Immune Function in Mice |
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Affiliation: | Xiong Pingyuan,et al(Department of Immunology,College of Medical Science,Wuhan University of Science and Technology,Wuhan 430065) |
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Abstract: | Objective: To understand the impact of ginkgo biloba extract on immune function.Methods: The in vitro antibody forming cells assay detection of Ginkgo biloba extract on mouse spleen cells to produce antibodies;by indirect immunofluorescence method for the determination of the Ginkgo biloba extract on mice of CD4+ / CD8+ T lymphocyte subsets Group impact;3H-TdR incorporation assay of Ginkgo biloba extract on lymphocyte transformation activity.Results: Ginkgo biloba extract to promote the role of the humoral immune function(P0.01);through the adjustment of the CD4+ / CD8+ T cell subsets in the ratio to enhance the immune function of mice(P0.05);to increase mouse lymphocyte transformation activity(P0.001).Conclusion: Ginkgo biloba extract can enhance immune function. |
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Keywords: | ginkgo biloba antibody-forming cells lymphocyte transformation T lymphocyte subsets |
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