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| 恶性血液病血清叶酸、维生素B_(12)的测定及其临床意义 | |
| 引用本文： | 黄淑桦,郭永炼,胡榕,黄增敏,辛碧珍,战榕,杨凤娥,傅丹辉,陈颖,吕联煌. 恶性血液病血清叶酸、维生素B_(12)的测定及其临床意义[J]. 福建医科大学学报, 1993, 0(4) |
| 作者姓名： | 黄淑桦 郭永炼 胡榕 黄增敏 辛碧珍 战榕 杨凤娥 傅丹辉 陈颖 吕联煌 |
| 作者单位： | 福建省血液病研究所(黄淑桦，郭永炼，黄增敏，傅丹辉)，福建医学院附属协和医院(胡榕，辛碧珍，战榕，杨凤娥，陈颖) |
| 摘 要： | 用放免分析法测定恶性血液187例血清叶酸(FA)值明显降低,151例血清维生素B_(12)(B_(12))值明显增高;化疗未缓解组(含部分缓解),血清FA虽有上升,B_(12)亦有下降,但与治疗前相比,无明显差异;完全缓解组FA明显上升,B_(12)值明显下降,与治疗前相比差异有显著性。对部分病例进行动态观察,进一步证实上述结果。提示血清FA,B_(12)含量与恶性血液病病情转归密切相关。 |
| 关 键 词： | 恶性血液病 白血病 血清叶酸 血清维生素B_(12) |
Clinical Significance of Serum Folic Acid and Vitamin B_(12) in Hematologic Malignancies |
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| Huang Shuhua,Guo Yonglian,Hu Rong Fujian Institute of Hematology,Fuzhou. Clinical Significance of Serum Folic Acid and Vitamin B_(12) in Hematologic Malignancies[J]. Journal of Fujian Medical University, 1993, 0(4) | |
| Authors: | Huang Shuhua Guo Yonglian Hu Rong Fujian Institute of Hematology Fuzhou |
| Abstract: | Serum folic acid and VitaminB_(12) (B_(12)) concentrations were measured with radioimmunoassay in patients with hematologic malignancies. The results showed that the serum folic acid value in 187 patients with hematologic malignancies was significantly decreased and the serum B_(12) value in 151 patients was elevated statistically. After chemotherapy the folic acid value in patients with partial or no remission was increased insignificantly and the B_(12) value was decreased, both were stutistically insignificant as compared with those before chemotherapy. However,in patients with complete remission the folic acid value was increased and the B_(12) value reduced significantly as compared with those before chemotherapy. Serial determinations suggest that the folic acid and B_(12) concentrations are closely correlated to the outcome of hematologic malignancies. |
| Keywords: | hematologic malignancies leukemia serum folic acid serum vitamin B_(12) |
| 本文献已被 CNKI 等数据库收录！ | |