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高效液相色谱法测定工人尿中三硝基甲苯及五种代谢物(二)——分析方法的建立及应用
引用本文:姚明,缐引林. 高效液相色谱法测定工人尿中三硝基甲苯及五种代谢物(二)——分析方法的建立及应用[J]. 卫生研究, 1991, 0(1)
作者姓名:姚明  缐引林
作者单位:中国预防医学科学院劳动卫生与职业病研究所,中国预防医学科学院劳动卫生与职业病研究所
摘    要:
本文建立了高效液相色谱(HPLC)测定工人尿中TNT及五种代谢物的方法。TNT、4-A、2-A、2,6-DA和2,4-DA的平均回收率66.6~95.0%,变异系数在2.1~10.6%之间,最小检测限为3.0~8.1μg/L尿。本方法已用于35个接触TNT工人尿样的分析。

关 键 词:三硝基甲苯  代谢物  高效液相色谱  尿

Determination of TNT and Its Five Metabolites in Urine of Workers by High Performance Liquid Chromatography(HPLC)(2)Development and Application of the Analystic Method
Yao Ming et al.. Determination of TNT and Its Five Metabolites in Urine of Workers by High Performance Liquid Chromatography(HPLC)(2)Development and Application of the Analystic Method[J]. Journal of hygiene research, 1991, 0(1)
Authors:Yao Ming et al.
Abstract:
The development of method for the determination of TNT and its five metabolites in urine of workers by HPLC is described in this paper. The average recoveries were 66. 6~95. 0% for TNT, 4-A, 2-A, 2, 6-DA and 2, 4-DA and their coefficients of variation were 2.1~10.6%. The minimum detectable limits of the five metabolites were 3.0~8.1~tg/L urine. This method has been applied for the analysis of 35 urine samples of the exposed workers.
Keywords:TNT   metabolite   HPLC   urnie
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