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HPLC法测定藿香正气胶囊中厚朴酚与和厚朴酚的含量
引用本文:孟蕾蕾,李梦,王国平.HPLC法测定藿香正气胶囊中厚朴酚与和厚朴酚的含量[J].齐鲁药事,2007,26(8):466-467.
作者姓名:孟蕾蕾  李梦  王国平
作者单位:日照市药品检验所,山东,日照,276826
摘    要:目的测定藿香正气胶囊中厚朴酚与和厚朴酚的含量.方法采用HPLC法.色谱柱:采用Thermo 1254133T色谱柱(250×4.6mm,5μm);流动相:甲醇-水(75∶25);流速:1.0mL·min-1;检测波长:294nm.结果厚朴酚平均回收率为99.81%,RSD=0.3%(n=5);和厚朴酚平均回收率为100.14%,RSD=0.8%(n=5).结论方法简单易行,结果准确,可靠,适用于本品的含量测定.

关 键 词:高效液相色谱法  藿香正气胶囊  厚朴酚  和厚朴酚  含量测定
文章编号:1672-7738(2007)08-0466-02

Determination of Magnolol and Honokiol in Huoxiang Zhengqi Capsule by HPLC
MENG Lei-lei,LI Meng,WANG Guo-ping.Determination of Magnolol and Honokiol in Huoxiang Zhengqi Capsule by HPLC[J].qilu pharmaceutical affairs,2007,26(8):466-467.
Authors:MENG Lei-lei  LI Meng  WANG Guo-ping
Institution:Rizhao institute for drug control, Rizhao 276826
Abstract:OBJECTIVE To set up a method for determination of magnolol and honokiol in Huoxiang Zhengqi capsule.METHODS HPLC method was adopted.The mobile phase was methanol-water(75∶25),the flow rate was 1.0ml·min-1,and the UV detection wavelength was 294nm.RESULTS Average recovery rate of magnolol was 99.81%,RSD was 0.3%(n=5);average recovery rate of honokiol was 100.14%,RSD was 0.8%(n=5).CONCLUSION The method is simple,accurate and suitable for the assay of magnolol and honokiol in Huoxiang Zhengqi capsule.
Keywords:HPLC  H uoxiang Zhengqi capsule  Magnolol  Honokiol  determination
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