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Clinical characteristics of upper airway resistance syndrome
Authors:Takuya Watanabe MD,Akira Mikami MD,Mitsutaka Taniguchi MD,Masamichi Motonishi MD,Hideharu Honda MD,Kyoko Kyotani MD,Shigehiko Uruha MD,Kiyoji Terashima MD,Yoshio Teshima MD,Isao Egawa MD,Yoshiro Sugita MD, &   Masatoshi Takeda MD
Affiliation:Department of Medical Science III, School of Health and Sport Sciences, Osaka University, Japan.
Abstract:Polysomnographic findings and clinical symptoms were investigated in 14 cases of upper airway resistance syndrome. The mean scores of the Epworth sleepiness scale and self-rating depression scale in eight cases were 13.5 and 38.6, respectively. The mean sleep latency of the multiple sleep latency test in four cases was 10.2 min. Seven cases were treated with continuous positive airway pressure (CPAP), and one with hormone replacement therapy. The most common symptom was daytime sleepiness. Five cases had hypertension. CPAP reduced increasing negative esophageal pressure (Pes) and frequency of EEG arousals, and improved hypertension in one case. Hormone replacement therapy ameliorated increasing negative Pes and clinical symptoms.
Keywords:continuous positive airway pressure    daytime sleepiness    electroencephalogram arousal    hormone replacement therapy    snoring    upper airway resistance syndrome
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