舟曲泥石流灾后中药汤剂预防腹泻和感冒的效果评价

目的:了解泥石流后灾区人群感冒及腹泻的发病状况,评价大规模使用中药汤剂对灾区人群感冒、腹泻的预防效果。方法:采用整群抽样的方法,抽取舟曲县独立初中二年级学生496名,分为试验组(278名)和对照组(218名),试验组每天服用防腹泻方及防感冒方各1次,对照组不服用任何药物。20d后,统计两组的感冒、腹泻发病率并进行两组间率的比较;全体试验人群进行血常规及相关免疫水平的检测:T淋巴细胞亚型(CD3+、CD4+、CD+8)检测、B淋巴细胞检测、NK淋巴细胞的流氏细胞检测。结果:CD+4/CD+8比值、血红蛋白两组比较有统计学意义(P值分别为0.04、0.00);CD3+、NK、B、全血红细胞两组比较无统计学意义(P值分别为0.62、0.45、0.60、0.57)。试验组感冒发病率为30.58%,腹泻发病率为16.55%;对照组感冒发病率为75.69%,腹泻发病率为34.40%。两组感冒发病率及腹泻发病率比较均有显著性差异(P0.01)。感冒保护率为59.60%,腹泻保护率为51.89%。感冒效果指数为2.48,腹泻效果指数为2.08。结论:中药汤剂防腹泻方和防感冒方可提高灾区灾民免疫力,降低感冒及腹泻的发病率,其机制可能与细胞免疫力的提高和血红蛋白的增加有关。

Effectiveness evaluation of the herbal soup in preventing diarrhoea and influenza after the debris flow in Zhouqu

Objective: To see the paroxysm of the population who had the cold and diarrheal after the debris flow,and to evaluate the effectiveness of drinking abundance of herbal soup in preventing the diarrhoea and influenza.Methods: Using cluster sampling method to extract independent Zhouqu County 496 junior high school sophomores whowere divided into experimental group(278 people) and the control group(218 people).The experimental group took daily doses of prevention diarrhea and cold soups each time,the control group did not take any medications.Tracing observation after 20 days,to calculate the incidence of diarrhea and cold of the two groups,and to compare rates between the two groups;And to detect the level of the blood and the related immune indexes of whole test population: T lymphocytes subsets(CD3+,CD4+,CD8+) detection,B lymphocytes detection,the flow’s cell detection of NK cells.Results: CD4+/ CD8+ ratio,hemoglobin between the two groups were statistically significant(P values were 0.04,0.00);CD3+,NK,B,red blood cells in whole blood between the two groups were not significant(P values were 0.62,0.45,0.60,0.57).The incidence of colds was 30.58%,the incidence of diarrhea was 16.55% in experimental group;And the incidence of colds was 75.69%,the incidence of diarrhea was 34.40% in control group.The incidence of colds of the two groups has significant difference(P<0.01),the incidence of diarrhea in the two groups has significant difference too(P<0.01).The protection rate of cold was 59.60%,the protection rate of diarrheawas 51.89%.The effect index of cold is 2.48,The effect index of diarrhea is 2.08.Conclusion: Chinese medicine decoction can improve the immune system of people in disaster-stricken areas,reduce the cold,the incidence of diarrhea,which may be related with the increase of cell-mediated immunity and hemoglobin.