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Treatment of ocular toxocariasis with albendezole: A case report
Authors:Marcela Frazier  Michelle L. Anderson  Sophocles Sophocleous
Affiliation:1. Research Institute for Infectious Diseases of Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran;2. Department of Medical Parasitology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran;1. Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran;2. Department of Pathology, Birjand University of Medical Sciences, Birjand, Iran;3. Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand;4. Centre for Tropical Medicine and Global Health, University of Oxford, UK;5. Department of Microbiology, Birjand University of Medical Sciences, Birjand, Iran;6. Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran;7. Department of Medical Parasitology and Mycology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran;1. Interdepartmental Program in Translational Biology and Molecular Medicine, National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA;2. BCM Medical Scientist Training Program, National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA;3. Department of Medicine, National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA;4. Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA;5. Department of Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA;1. Centro de Desenvolvimento Tecnológico/Biotecnologia, Universidade Federal de Pelotas, CP 354, CEP 96010-900, Pelotas, RS, Brasil;2. Faculdade de Medicina/Laboratório de Parasitologia, Universidade Federal de Rio Grande, General Osório, S/N, CEP 96200-190, Rio Grande, RS, Brasil;3. Faculdade de Nutrição, Universidade Federal de Pelotas, CP 354, CEP 96010-900, Pelotas, RS, Brasil
Abstract:BackgroundToxocara canis is a parasite that can infect the eye and create a significant inflammatory response that can be detrimental to the patient's vision. Its clinical presentation can mimic other causes of uveitis, and its diagnosis and treatment can be challenging. Prompt and accurate diagnosis of ocular toxocariasis is essential to prevent permanent visual loss.Case ReportA 7-year-old Hispanic boy presented to the clinic with complaints of reduced visual acuity in the left eye. After a careful evaluation of his ocular health, he had ocular toxocariasis diagnosed and confirmed by enzyme-linked immunosorbent assay testing. Treatment with the anthelmintic, albendazole, and oral steroids was initiated. There was initial improvement of the vitritis with significant vitreous debris. However, 2 years later, reactivation occurred, and a vitrectomy was required. This case report reviews the management of a patient with active ocular toxocariasis, including clinical findings and treatment options.ConclusionsThe differential diagnosis of ocular toxocariasis and review of the available treatments are presented.
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