血同型半胱氨酸水平对急性心肌梗死介入治疗预后的影响

目的探讨血同型半胱氨酸（HCY）水平对急性心肌梗死（AMI）患者急诊经皮冠状动脉介入治疗（PCI）预后的影响。方法入选接受急诊PCI的AMI患者86例，根据血HCY水平分为高同型半胱氨酸血症（HHcy）组（37例）和对照组（49例），两组均给予PCI术后常规治疗，并进行为期6个月的术后随访，分析随访期间的主要心血管事件（MACE）与HCY水平的相关性。结果与对照组比较，HHcy组MACE发生率明显高于对照组，差异具有统计学意义（P=0.011）；结论血HCY水平与急诊PCI术后的MACE发生率密切相关，是其预后的独立预测因素。

Effects of homocysteine level in patients treated with emergency ercutaneous coronary intervention for acute myocardial infarction

Objective To investigate the effects of homocysteine （HCY） level in patients treated with emergency percutaneous coronary intervention （PCI） for acute myocardial infarction （AMI）. Methods 86 consequent AMI patients treated with emergency PCI were divided into HHCY group （n=37） and control group （n=49）. and the maior adverse cardiac events （MACE） during at 6 months of follow-up were compared between the two groups and analyzed for their association with Hcy level. Results At 6 months of follow-up,tincidence of MACE of HHcy groups was significantly higher （P=0.011） than that of control groups. Conclu-sion Blood HCY levels are closely correlated with the incidence of MACE following emergency PCI ,and it may be the indepen-dent predictor factor for prognosis.