613例早期胃癌的临床病理特点分析

目的：了解我院早期胃癌的临床病理特点。方法回顾性统计我院内镜中心2007年至2010年4年来内镜诊断的早期胃癌，分析早期胃癌在同期胃癌病例中的构成比及其临床病理特点。结果从2007年至2010年共行胃镜检查124142例，检出胃癌共5493例，胃癌检出率为4.4%。早期胃癌613例，占胃癌的11.2%。自2007年至2010年胃癌的检出率分别是5.17%、4.72%、4.39%、3.80%；其中早期胃癌的构成比分别为7.4%、11.6%、12.2%、12.8%。可见胃癌总体内镜下检出率呈下降趋势，而早期胃癌占胃癌的构成比呈上升趋势。所有检出的早期胃癌平均发病年龄为（51±14.5）岁。男：女为1.85：1，男性明显多于女性（P〈0.05）。早期胃癌胃窦部最常见，占66%，然后依次是胃体24%、贲门胃底5.6%、残胃4.0%。胃窦早期胃癌显著多于其它部位（P〈0.05）。按照病理结果，管状腺癌、乳头状腺癌、低分化腺癌、黏液腺癌、印戒细胞癌构成比分别为20.8%、23.7%、38.2%、16.8%、0.6%。根据内镜下表现，将早期胃癌分为隆起型、浅表型和凹陷型，其构成比分别是12.6%、28.6%、58.9%。结论随着内镜技术的进步，早期胃癌的发现比率增多。早期胃癌的好发部位、病理特点和进展期胃癌类似。

Clinicopathological characteristics of 613 patients with early gastric cancer

Objective To research the clinicopathological characteristics of patients with early gastric cancer （EGC） in our hospital. Methods We investigated retrospectively patients with EGC which was diagnosed by endoscope in our hospital from 2007 to 2010,and analyzed the constituent ratio of EGC in gastric cancer in the same period and its clinicopathological character-istics. Results The 5493 patients with gastric cancer were diagnosed in 124142 patients recieved gastroscopy from 2007 to 2010. The check-out rate was 4.4%.There were 613 patients （11.2%） with EGC in all with gastric cancer. The check-out rate of gastric cancer each year were 5.17%,4.72%,4.39% and 3.80% respectively. The constituent ratio of EGC each year were 7.4%,11.6%, 12.2% and 12.8% respectively. The check-out rate of gastric cancer decreased,but the constituent ratio of EGC in gastric cancer increased. Average age of patients with EGC was 51±14.5 year old. Ratio of males to females was 1.85：l,and male patients were obviously more than female （P〈0.05）. The antrum was the most location of EGC （66%）,then body of stomach （24%）,cardia and fundus of stomach（5.6%）,gastric remnant（4.0%）. The constituent ratio of well-differentiated adenocarcinomas,poorly differentiated adenocarcinoma,moderately differentiated adenocarcinoma,signetring cell carcinoma and myxoadenocarcinoma in EGC were 20. 8%,23.7%,38.2%,16.8%and 0.6%respectively. The constituent ratio of protruding,flat and depressed type of EGC were 12.6%,28.6%and 58.9%respectively. Conclusion The check-out rate of EGC increased along with the progress of the endoscopic tech-nology. The primary sites and pathological characteristics of EGC were similar to advanced gastric cancer.