Simodont系统辅助照明条件对口腔临床技能训练的影响

目的探讨Simodont虚拟仿真系统中虚拟涡轮机机头的辅助光照对实际操作的影响，为口腔临床技能训练提供指导。 方法选取四川大学华西口腔医学院口腔医学专业本科生56人为研究对象，按随机数表法随机分为两组，实验组（虚拟仿真牙科训练机的涡轮机头的辅助灯处于打开状态）和对照组（虚拟仿真牙科训练机的涡轮机头的辅助灯处于关闭状态）的学生分别使用Simodont虚拟仿真系统在不同辅助光照情况下进行练习和考核，并在临床冷光灯条件下使用玻璃板模拟临床操作，采用t检验对比分析两组的得分。并通过问卷调查了解学生的使用体验。 结果不同辅助光照条件下，Simodont虚拟训练机操作总分（t = 1.342，P = 0.181）和临床冷光灯条件下玻璃板的操作结果（t = -0.585，P = 0.561）差异均无统计学意义；但Simodont总分构成项中"Leeway sides（洞缘偏差）"项有光组学生分数为5.38 ± 4.69，大于无光组分数（4.32 ± 2.92），差异有统计学意义（t = 2.252，P = 0.025）。 结论尚不能认为Simodont系统在有辅助灯的条件下可以影响医学生的培训效果，但在有辅助照明的情况下操作可能更容易误碰到规定区域边界的侧方。问卷结果显示，Simodont虚拟仿真系统是一种值得推广的教学模式。     

Human mast cells present antigen to autologous CD4+ T cells

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中医色诊图像采集系统的设计与实现及实验研究

研制中医色诊图像采集系统.整体制作为箱体式上下结构,系统选择色温5500K的氙灯模拟日光光源,反射率大于96％的聚四氟乙烯悬浮树脂涂层积分球漫射照明,分辨率为4 752像素×3 168像素的调谐数码相机采集图像.长时间光源稳定性和光线均匀性实验表明:图像采集系统光源稳定性大于99.1％、显色性大于95％,光线均匀性大于98.6％;不同照度下,图像色度偏差小于1.24％;40例中青年和60例老年人面部图像采集实验证明:面部图像采集系统可以用RGB和Lab颜色空间的数据准确定量人脸面部的特征色诊信息,采集的数据可为中医色诊信息的客观化研究提供参考.     

几种超分辨率荧光显微技术

传统的光学显微技术受限于瑞利/阿贝准则无法分辨出200 nm以下的结构,而超分辨率荧光显微技术能突破衍射极限对亚细胞结构进行观测.这些超分辨率荧光显微技术大体上可以分为3类:①基于结构光照明的超分辨率成像技术,如受激发射损耗显微技术和饱和结构照明显微术;②基于单分子定位的超分辨率成像技术,如随机光学重构显微术和光激活定位显微术;③基于漂白、闪烁的超分辨率成像技术.本文了上述3类超分辨率荧光显微技术提高成像分辨率的方法及应用,并对其发展趋势进行展望.     

Colour rendering of indoor lighting with CIE illuminants and white LEDs for normal and colour deficient observers

The goal of this work was to evaluate the colour rendering of indoor lighting with CIE illuminants and white LEDs by estimating the chromatic diversity produced for normal and colour deficient observers. Reflectance spectra of a collection of scenes made of objects typically found indoors were obtained with hyperspectral imaging. Chromatic diversity was computed for 55 CIE illuminants and five LED light sources by estimating the number of different colours perceived in the scenes analysed. A considerable variation in chromatic diversity was found across illuminants, with the best producing about 50% more colours than the worst. For normal observers, the best illuminant was CIE FL3.8 which produced about 8% more colours than CIE illuminant A and D₆₅; for colour deficient observers, the best illuminants varied with the type of deficiency. When the number of colours produced with a specific illuminant was compared against its colour rendering index (CRI) and gamut area index (GAI), weak correlations were obtained. Together, these results suggest that normal and colour deficient observers may benefit from a careful choice of the illuminant, and this choice may not necessarily be based only on the CRI or GAI.     

静脉用药集中调配中心紫外灯消毒对洁净度的影响

目的：验证静脉用药集中调配中心（PIVAS）洁净环境中紫外灯是否需要开启以及其对局部洁净环境洁净度的影响,为实际工作应用提供参考。方法：选取紫外灯辐射照度合格的不同型号洁净层流台,紫外灯开启不同时长,检测洁净度相关参数变化情况。结果：紫外灯两端辐射照度明显小于中央处,不同型号洁净操作台紫外灯台面照度差异较大;紫外灯无论是否开启或开启多长时间,相关洁净度参数如风速、悬浮粒子数、沉降菌及表面取样培养均符合标准要求。结论：在洁净层流环境中,紫外灯开启与否,不会对洁净环境的洁净度造成影响。主要影响输液调配质量的应为无菌操作环节,加强无菌操作标准化、规范化培训应作为PIVAS工作的重点。     

Evaluation of BreastLight as a Tool for Early Detection of Breast Lesions among Females Attending National Cancer Institute,Cairo University

Background: Breast illumination was suggested as a simple method for breast cancer screening. BreastLightis a simple apparatus for this purpose. Objective: To evaluate the diagnostic performance of BreastLight as ascreening tool of breast cancer in comparison to mammography and histopathology. Materials and Methods: Thishospital-based cross sectional study was conducted in the mammography unit of the radiodiagnosis departmentat National Cancer Institute, Cairo University. All participants were subjected to breast examination with theBreastLight tool, mammography and ultrasonography. Suspicious cases were biopsied for histopathologicalexamination which is considered as a gold standard. Results: The mean age of the participants was 46.3±12.4years. Breast illumination method had sensitivity, specificity, positive predictive value, negative predictivevalue and total accuracy of 93.0%, 73.7%, 91.4%, 77.8% and 88.2%, respectively in detection of breast cancer.Conclusions: Breast illumination method with BreastLight apparatus is a promising easy-to-use tool to screen forbreast cancer suitable for primary health care physician or at-home use. It needs further evaluation especiallyin asymptomatic women.