全文获取类型
收费全文 | 5344篇 |
免费 | 445篇 |
国内免费 | 72篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 299篇 |
妇产科学 | 985篇 |
基础医学 | 1133篇 |
口腔科学 | 24篇 |
临床医学 | 1382篇 |
内科学 | 298篇 |
皮肤病学 | 22篇 |
神经病学 | 235篇 |
特种医学 | 71篇 |
外科学 | 155篇 |
综合类 | 476篇 |
现状与发展 | 1篇 |
一般理论 | 2篇 |
预防医学 | 578篇 |
眼科学 | 16篇 |
药学 | 133篇 |
2篇 | |
中国医学 | 12篇 |
肿瘤学 | 34篇 |
出版年
2024年 | 15篇 |
2023年 | 115篇 |
2022年 | 175篇 |
2021年 | 221篇 |
2020年 | 237篇 |
2019年 | 238篇 |
2018年 | 210篇 |
2017年 | 219篇 |
2016年 | 271篇 |
2015年 | 232篇 |
2014年 | 313篇 |
2013年 | 467篇 |
2012年 | 312篇 |
2011年 | 282篇 |
2010年 | 250篇 |
2009年 | 227篇 |
2008年 | 201篇 |
2007年 | 197篇 |
2006年 | 177篇 |
2005年 | 148篇 |
2004年 | 151篇 |
2003年 | 129篇 |
2002年 | 105篇 |
2001年 | 84篇 |
2000年 | 55篇 |
1999年 | 77篇 |
1998年 | 83篇 |
1997年 | 47篇 |
1996年 | 64篇 |
1995年 | 36篇 |
1994年 | 39篇 |
1993年 | 48篇 |
1992年 | 44篇 |
1991年 | 38篇 |
1990年 | 27篇 |
1989年 | 22篇 |
1988年 | 32篇 |
1987年 | 22篇 |
1986年 | 24篇 |
1985年 | 48篇 |
1984年 | 42篇 |
1983年 | 16篇 |
1982年 | 15篇 |
1981年 | 25篇 |
1980年 | 28篇 |
1979年 | 22篇 |
1978年 | 14篇 |
1977年 | 6篇 |
1971年 | 3篇 |
1970年 | 4篇 |
排序方式: 共有5861条查询结果,搜索用时 10 毫秒
1.
2.
Sarah L Barber 《International journal for quality in health care》2006,18(4):306-313
OBJECTIVE: To evaluate variations in prenatal care quality by public and private clinical settings and by household wealth. DESIGN: The study uses 2003 data detailing retrospective reports of 12 prenatal care procedures received that correspond to clinical guidelines. The 12 procedures are summed up, and prenatal care quality is described as the average procedures received by clinical setting, provider qualifications, and household wealth. SETTING: Low-income communities in 17 states in urban Mexico. PARTICIPANTS: A total of 1253 women of reproductive age who received prenatal care within 1 year of the survey. MAIN OUTCOME MEASURE: The mean of the 12 prenatal care procedures received, reported as unadjusted and adjusted for individual, household, and community characteristics. RESULTS: Women received significantly more procedures in public clinical settings [80.7, 95% confidence interval (CI) = 79.3-82.1; P < or = 0.05] compared with private (60.2, 95% CI = 57.8-62.7; P < or = 0.05). Within private clinical settings, an increase in household wealth is associated with an increase in procedures received. Care from medical doctors is associated with significantly more procedures (78.8, 95% CI = 77.5-80.1; P < or = 0.05) compared with non-medical doctors (50.3, 95% CI = 46.7-53.9; P < or = 0.05). These differences are independent of individual, household, and community characteristics that affect health-seeking behavior. CONCLUSIONS: Significant differences in prenatal care quality exist across clinical settings, provider qualifications, and household wealth in urban Mexico. Strategies to improve quality include quality reporting, training, accreditation, regulation, and franchising. 相似文献
3.
Thomas James Zirpoli Patricia Mulhearn Blasco 《Journal of developmental and physical disabilities》1988,1(1):69-77
Current medical procedures used in prenatal screening and diagnosis of handicapping conditions are reviewed. These strategies include ultrasound, amniocentesis, chorionic villus biopsy, restriction enzyme analysis, maternal serum analysis, fetoscopy, and fetal serum analysis. Along with an explanation of each method, advantages, disadvantages, and risks involved with each are provided. An understanding of these procedures by medical and educational personnel is encouraged, and the potential benefits of prenatal identification of handicapping conditions are emphasized. 相似文献
4.
Objective To establish a means for prenatal prediction of spinal muscular atrophy (SMA) through survival motor neuron (SMN) gene deletion analysis and genetic counseling in families with a child affected with SMA.
Methods Genetic analysis for prenatal prediction of Werdnig-Hoffmann disease was performed in a at risk Chinese family by polymerase chain reaction (PCR)-single-strand conformation polymorphism (SSCP) in SMN gene exons 7 and 8.
Results The pregnancy was positive for the homozygous deletion of the SMN gene, thus the fetus was diagnosed as being affected and the pregnancy was terminated.
Conclusion This approach is fast and reliable for DNA-based prenatal diagnosis of Werdnig-Hoffmann disease. 相似文献
Methods Genetic analysis for prenatal prediction of Werdnig-Hoffmann disease was performed in a at risk Chinese family by polymerase chain reaction (PCR)-single-strand conformation polymorphism (SSCP) in SMN gene exons 7 and 8.
Results The pregnancy was positive for the homozygous deletion of the SMN gene, thus the fetus was diagnosed as being affected and the pregnancy was terminated.
Conclusion This approach is fast and reliable for DNA-based prenatal diagnosis of Werdnig-Hoffmann disease. 相似文献
5.
Kenji Shimada Fumi Matsumoto Mari Kawagoe Futoshi Matsui 《International journal of urology》2007,14(5):388-392
OBJECTIVE: It is well described that unilateral pelviureteric junction obstruction (PUJO) is a benign condition, because the dilatation resolves spontaneously and the function does not decrease in most of the kidneys. However, there is exceptional PUJO that requires emergent treatment in neonatal periods. The aim of this article is to report the urological emergency and management in neonates with PUJO. MATERIALS AND METHODS: Nine children (seven boys and two girls) with PUJO who underwent neonatal emergent treatment during the last 13 years were reviewed. Renal function was evaluated according to decay curve of serum creatinine (SCr) levels corresponding to gestational age (GA) at delivery. Physical examination, ultrasonographic monitoring, and chest and abdominal plain radiographs were repeated in each neonate. RESULTS: Eight patients were detected prenatally. In five patients, multicystic dysplastic kidney (MCDK) was demonstrated on the contralateral side. Three patients underwent percutaneous puncture of fetal hydronephrosis. Decrease of amniotic fluid was evident in three fetuses. Indications for emergent treatment included mass effect from hydronephrosis in three patients, renal dysfunction in five, and severe urinary tract infection in one. During neonatal periods, a percutaneous nephrostomy tube was placed in seven, and open nephrostomy in one with anorectal malformation. Repeated punctures of the dilated renal pelvis were done in one patient. Renal function after pyeloplasty was stable in eight patients, while it was moderately decreased in one who was associated with oligohydramnios in utero. CONCLUSION: Indications for emergent treatment in neonates with PUJO included mass effect from giant hydronephrosis, renal dysfunction and severe urinary tract infection. At birth, respiratory and circulatory conditions must first be stabilized. In neonates with hydronephrosis of the solitary kidney or severe bilateral PUJO, serial SCr should be monitored to evaluate renal function. Decrease of amniotic fluid suggested renal functional compromise that would not recover after urological management. 相似文献
6.
Masako Nishizuka Hiroyuki Sumida† Yasuhiko Kano† Yasumasa Aral 《Journal of neuroendocrinology》1993,5(5):569-573
An examination was made of neurogenesis in the anteroventral periventricular nucleus (AVPv) of the preoptic area of the rat using bromodeoxyuridine (BrdU), a thymidine analog, and a BrdU-specific antibody. Cells in the AVPv of adult rats were labeled with the antibody when BrdU was injected into pregnant rats once during day 13 to 18 of gestation, but not during day 10 to 12 nor 19 to 20 of gestation nor on postnatal day 1, indicating that neurogenesis of the AVPv occurs during a limited period from day 13 to 18 of gestation. Next, to examine the effects of androgen on neurogenesis, BrdU was injected once on day 15 into pregnant rats that also received injections of testosterone propionate (TP). The number of BrdU-labeled cells in the AVPv was similar in control female and male fetuses and female fetuses from pregnant rats that received daily injections of TP during days 14 to 16, when fetuses were examined on day 17 of gestation. These results suggest that the neurogenesis that was recognized by labeling with BrdU was not affected by the treatment with TP. On day 21 of gestation, BrdU-labeled cells in the AVPv of control male fetuses and female fetuses that received TP during days 14 to 18 were fewer in number than those in female fetuses of the control group, whereas treatments with TP during days 14 to 16 and during days 17 to 18 did not cause any significant decrease in number of BrdU-labeled cells. These findings support the hypothesis that elimination of a population of cells, for example, by cell death as described previously, is enhanced in male fetuses and in female fetuses treated with TP repetitively. 相似文献
7.
Xenofon Giannakopoulos Panagiotis Chambilomatis loannis Filiadis Agathi Ntourntoufi Styliani Andronikou Alciviadis Kammenos 《International journal of urology》1997,4(3):324-326
Torsions of the spermatic cord occurring from the intrauterine period to the end of the first year of life are termed perinatal. These are divided into prenatal and postnatal torsions, depending on their occurrence in the intrauterine or postuterine period. From January 1984 to January 1996, 6 cases were identified at our institution, involving 4 prenatal and 2 postnatal extravaginal torsions of the spermatic cord. These cases are reviewed with regard to optimal therapeutic approaches for the treatment of both the affected gonad as well as the contralateral one, and whether the event occurred prenatally or postnatally. The authors also propose several clinical indications useful for obstetricians, pediatricians, urologists and nurses. 相似文献
8.
孕妇血清AFP、uE3和β-hCG水平与严重胎儿缺陷的关系 总被引:3,自引:0,他引:3
①目的 探讨孕中期血清甲胎球蛋白(AFP),游离雌三醇(uF3)和β绒毛膜促性腺激素(β-HCG)水平与严重胎儿缺陷的关系。②方法 用ELISA方法对832例16-21周妊娠妇女血清AFP、UE3和β-hCG进行检测,以筛查阳性病人。③结果 14例胎儿被确诊为异常,其中唐氏综征2例,无脑儿3例,脊柱裂3例,唇腭裂1例,腹裂肠外翻1例,孕中期自然流产2例,死胎1例,葡萄胎1例,总检出率为1.68%,假阳性15例,占被检人数的1.80%。④结论 以上3种生化指标联合检测可作为产前诊断严重胎儿缺陷的有效方法。 相似文献
9.
10.