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Samy Egli Michael Riedel Hans-Jürgen Möller Anton Strauss Damian Läge 《European archives of psychiatry and clinical neuroscience》2009,259(3):164-171
Background In the current debate about the categorical or dimensional classification of mental disorders many fruitful methods to illustrate
one or the other aspect are employed, and suggestions are made to combine the two perspectives.
Methods We present such an approach to combine both perspectives at the same time. Based on psychopathological AMDP-symptom profiles,
a map of psychiatric patients was calculated by robust nonmetric multidimensional scaling (NMDS).
Results The sample from the Ludwig-Maximilians University in Munich included the records of patients, who were admitted and discharged
in 2002 and 2003 with a diagnosis of either paranoid schizophrenia, (F20.00, N = 24), bipolar affective disorder, current episode manic without psychotic symptoms (F31.1, N = 32) or severe depressive episode without psychotic symptoms (F32.2, N = 78). In the resulting map of patients we found a clear categorical distinction according to the diagnostic groups, but
also high regression values of AMDP-syndromes (manic syndrome: r = 0.83, depressive syndrome: r = 0.68, and paranoid-hallucinatory syndrome, r = 0.62).
Discussion The map of psychiatric patients presents an approach to consider the categorical and dimensional aspects at the same time.
We were able to identify meaningful delineations between diagnostic clusters as well as continuous transitions. This method
allows the whole psychopathological profile of each individual patient to be considered and also to identify misdiagnosed
cases at a glance. 相似文献
2.
Winkler D Pjrek E Heiden A Wiesegger G Klein N Konstantinidis A Kasper S 《European archives of psychiatry and clinical neuroscience》2004,254(4):209-214
Abstract.
In the last few years there has been increased
scientific effort to describe the gender–specific
psychopathological features of depression. Until now
these studies have not been entirely conclusive, which
could be the result of methodological difficulties. This
report investigates sex differences in the symptom presentation
in an inpatient population: 104 female and 113
male patients suffering from a depressive episode according
to ICD–10 were admitted to the inpatient treatment
at the Department of General Psychiatry in Vienna.
A psychopathological rating according to the
standardized documentation system of the AMDP (Association
for Methodology and Documentation in Psychiatry)
was performed at admission and discharge. At
admission into the hospital women tended to show more
affective lability (p = 0.025), whereas men had higher
scores in affective rigidity (p = 0.032), blunted affect
(p = 0.002), decreased libido (p = 0.028), hypochondriasis
(p = 0.016) and hypochondriac delusions (p = 0.039).
At discharge from the hospital women had significantly
higher scores in dysphoria (p = 0.010), while men were
more prone to have compulsive impulses (p = 0.030). Although
our results were obtained in a selected sample of
inpatients at a university hospital, they are indicative of
psychopathological differences between men and
women in the core symptoms of depression. These differences
may influence diagnostic practice and gender
specific treatment of depression.*Both authors contributed equally 相似文献
3.
Gerd Krüger Imme Haubitz 《European archives of psychiatry and clinical neuroscience》1980,228(4):299-315
Summary Cluster analysis was carried out on a sample of 92 patients with behavior disorders caused by degenerative, vascular, (alcohol) toxic, and other diseases of the brain. Rating variables of the AMDP system concerning mental state, social behavior, need for special care, sleep disorders, autonomic, physical, and neurologic symptoms were used in the absence of severe degrees of disordered consciousness such as stupor, coma, delirium tremens, and gross cerebral lesions. Results suggested the existence of four major groups of global cognitive impairment combined with neurasthenia and irritability in the first, hypochondriasis and depression in the second, withdrawal symptoms in the third, and severe disorientation in the fourth. At the seven-group level the groups were further distinguished according to severe withdrawal, amnestic syndrome, and dementia by various social and illness behaviors, sleep-wakefulness pattern, hypo- or hyperactivity, additional physical, and neurologic symptoms. Other minor types of organic brain syndromes were identified as individual cases by hallucinations or other circumscribed cognitive, psychomotor, affect, motivation, personality, and/ or behavior disorder, symptomatic manic, or schizophreniform psychosis. The findings lent support to old classifications and new ones of organic mental syndromes (DSM-III).This paper is dedicated to Professor Schrappe for his birthday and moving-in to the new Clinical Department of Psychiatry, Füchsleinstraße 15 相似文献
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