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Higuchi Takashi Sugisawa Norihiko Yamamoto Jun Oshiro Hiromichi Han Qinghong Yamamoto Norio Hayashi Katsuhiro Kimura Hiroaki Miwa Shinji Igarashi Kentaro Tan Yuying Kuchipudi Shreya Bouvet Michael Singh Shree Ram Tsuchiya Hiroyuki Hoffman Robert M. 《Cancer chemotherapy and pharmacology》2020,85(2):285-291
Cancer Chemotherapy and Pharmacology - Cancers are methionine (MET) and methylation addicted, causing them to be highly sensitive to MET restriction. The present study determined the efficacy of... 相似文献
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A 1:1 adduct of methyl sorbate (MS) and 1,3‐di‐tert‐butylimidazol‐2‐ylidene (NHCtBu) initiates anionic polymerization of a nonconjugated polar alkene, allyl methacrylate (AMA) in toluene at ?20 °C. After the monomer is consumed quantitatively using a bulky aluminum Lewis acid, methylaluminum bis(2,6‐di‐tert‐butyl‐4‐methylphenoxide) (MAD), as an additive, successive ring‐closure occurs without highly dilute conditions to give a cyclic poly(AMA) containing α‐terminal MS unit, and an Mn of 8.8 × 103?58.5 × 103 with a narrow molecular dispersity index (Mw/Mn = 1.14–1.37). The lack of a need for dilution is due to the fact that an α‐terminal NHCtBu group is acting as the counter cation for the propagating center in the polymerization. From 1H NMR and matrix assisted laser desorption/ionization (MALDI‐TOF) mass spectra, combined with transmittance electron microscope (TEM) observation of a synthesized poly(AMA) with longer alkyl side chains prepared via a thiol‐ene click reaction, it is concluded that once the monomer is consumed, nucleophilic attack at the neighboring methine of the α‐terminal NHCtBu residue by the propagating anionic center causes ring‐closing to cyclic poly(AMA). 相似文献
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Nobuaki Mori Narito Kagawa Akiko Higuchi Yasuko Aoki Kiyofumi Ohkusu 《Journal of clinical microbiology》2015,53(7):2378-2380
We report the first case of sepsis with enterocolitis that was caused by a novel urease-positive Helicobacter species in a young man. The isolate was characterized via 16S rRNA gene sequencing and their biochemical properties, and the patient was successfully treated with short-term antimicrobial therapy; no recurrence was observed. 相似文献
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Post‐operative infection of endoscopic submucosal dissection of early colorectal neoplasms: a case–controlled study using a Japanese database 下载免费PDF全文
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Ryuichi Iwakiri Kiyohito Tanaka Takuji Gotoda Shiro Oka Takao Ohtsuka Yasuhisa Sakata Toshimi Chiba Kazuhide Higuchi Hironori Masuyama Ryoichi Nozaki Koji Matsuda Nobuyuki Shimono Kazuma Fujimoto Hisao Tajiri 《Digestive endoscopy》2019,31(5):477-497
As part of the activities toward standardizing endoscopy procedures, the Japan Gastroenterological Endoscopy Society has prepared guidelines for cleansing and disinfection of gastrointestinal endoscopes. The environment of gastrointestinal endoscopy differs between Japan and advanced Western countries. In advanced Western countries, gastrointestinal endoscopy is performed almost exclusively at specialized facilities, where strict provisions are observed for cleansing and disinfecting endoscopes. In Japan, however, gastrointestinal endoscopy is performed even in small clinics, and the annual number of gastrointestinal endoscopy cases is enormous. In addition, the method for cleansing and disinfecting endoscopes differs among hospitals. Although there is a distinct lack of evidence for how gastrointestinal endoscopes are cleaned and disinfected, it is necessary to standardize the method for doing so to advance the field of endoscopic medicine. 相似文献
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Kadarkarai Murugan Narayanan Aarthi Kalimuthu Kovendan Chellasamy Panneerselvam Balamurugan Chandramohan Palanisamy Mahesh Kumar Duraisamy Amerasan Manickam Paulpandi Ramachandran Chandirasekar Devakumar Dinesh Udaiyan Suresh Jayapal Subramaniam Akon Higuchi Abdullah A. Alarfaj Marcello Nicoletti Heinz Mehlhorn Giovanni Benelli 《Parasitology research》2015,114(10):3657-3664
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