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排序方式: 共有485条查询结果,搜索用时 46 毫秒
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Clovis Arcoverde Freitas-Neto Fernando Oréfice Rogerio A. Costa Juliana L. Oréfice Swetha Dhanireddy Armin Maghsoudlou 《Seminars in ophthalmology》2016,31(5):495-498
To describe how a multifocal fundus imaging system assisted the early diagnosis of cat scratch neuroretinitis in a case of a 27-year-old male with unilateral visual loss, neuroretinitis, and a peripapillary angiomatous lesion. Multimodal fundus imaging analysis was an essential contributor to the clinical diagnosis of cat scratch neuroretinitis during the early stage of the disease. 相似文献
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Jorge Henrique Paiter Nascimento Rafael Lessa da Costa Luiz Fernando Nogueira Simvoulidis Joo Carlos de Pinho Roberta Santos Pereira Andrea Dornelles Porto Eduardo Costa de Freiras Silva Liszt Palmeira Oliveira Max Rogerio Freitas Ramos Glucia Maria Moraes de Oliveira 《Arquivos brasileiros de cardiologia》2021,116(2):275
BackgroundThe incidence of myocardial injury (MI) in patients with COVID-19 in Brazil and the prognostic impact of MI have not been elucidated.ObjectivesTo describe the incidence of MI in patients with COVID-19 in the intensive care unit (ICU) and to identify variables associated with its occurrence. The secondary objective was to assess high-sensitivity troponin I as a predictor of in-hospital mortality.MethodsRetrospective, observational study conducted between March and April 2020 with cases of confirmed COVID-19 admitted to the ICU. Numerical variables were compared by using Student t test or Mann-Whitney U test. The chi-square test was used for categorical variables. Multivariate analysis was performed with variables associated with MI and p<0.2 to determine predictors of MI. The ROC curve was used to determine the troponin value capable of predicting higher in-hospital mortality. Survival functions were estimated by use of the Kaplan-Meier method from the cut-off point indicated in the ROC curve.ResultsThis study assessed 61 patients (63.9% of the male sex, mean age of 66.1±15.5 years). Myocardial injury was present in 36% of the patients. Systemic arterial hypertension (HAS) [OR 1.198; 95%CI: 2.246-37.665] and body mass index (BMI) [OR 1.143; 95%CI: 1.013-1.289] were independent risk predictors. High-sensitivity troponin I >48.3 ng/mL, which was determined in the ROC curve, predicts higher in-hospital mortality [AUC 0.786; p<0.05]. Survival in the group with high-sensitivity troponin I >48.3 ng/mL was lower than that in the group with values ≤48.3 ng/dL [20.3 x 43.5 days, respectively; p<0.05].ConclusionThere was a high incidence of MI in severe COVID-19 with impact on higher in-hospital mortality. The independent risk predictors of MI were SAH and BMI. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0) 相似文献
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Kate McGirr Stine Ibsen Harring Thomas Sean Risager Kennedy Morten Frederik Schuster Pedersen Rogerio Pessoto Hirata Kristian Thorborg Thomas Bandholm Michael Skovdal Rathleff 《International Journal of Sports Physical Therapy》2015,10(3):332-340
Background
Home‐exercise is commonly prescribed for rehabilitation of the shoulder following injury. There is a lack of technology available to monitor if the patient performs the exercises as prescribed.Purpose
The purpose of this study was to investigate the validity of using three dimensional (3D) gyroscope data recorded with the Bandcizer™ sensor to differentiate between three elastic band exercises performed in the shoulder joint: abduction, flexion, and external rotation.Design
Concurrent validity study.Methods
This study was performed over two phases. In the first phase, 20 subjects performed three sets of 10 of shoulder abduction, external rotation and flexion exercises with a Thera‐Band mounted with a Bandcizer, while supervised by a physical therapist. The Bandcizer has an inbuilt three‐dimensional gyroscope, capable of measuring angular rotation. Gyroscope data were analyzed in Matlab, and a one‐way ANOVA was used to test for significant differences between each of the three exercises. An algorithm was then created in Matlab based on the exercise‐data from the gyroscope, to enable differentiation between the three shoulder exercises. Twenty new subjects were then recruited to cross‐validate the algorithm and investigate if the algorithm could differentiate between the three different shoulder exercises.Results
A blinded assessor using the Matlab algorithm could correctly identify 56 out of 60 exercise sets. The kappa agreement for the three exercises ranged between 0.86‐0.91.Conclusion
The ability to differentiate between the home exercises performed by patients after shoulder injury has great implications for future clinical practice and research. When home exercises are the treatments‐of‐choice, clinicians will be able to quantify if the patient performed the exercise as intended. Further research should be aimed at investigating the feasibility of using the Bandcizer™ in a home‐based environment.Word count
2429Level of Evidence
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Luciana Carvalho Moura Priscilla Caroliny de Oliveira Juliana Guareschi dos Santos Heloisa Barboza Paglione Jose Maria do Nascimento Neto Roberta Cristina Cardoso dos Santos Marli Cristina de Oliveira Marcos André Ramos Carneiro Felipe Alves Moreira Dayana Aparecida Martins Correa Calado Renata Fabiana Leite Bartira de Aguiar Roza Paolo Rogerio de Oliveira Salvalaggio Ana Cristina Carvalho de Matos 《Clinical transplantation》2015,29(12):1047-1053
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Gabriela Hädrich Gustavo Richter Vaz Michelle Maidana Jadel Muller Kratz Gecioni Loch-Neckel Daniely Cornélio Favarin Alexandre de Paula Rogerio Flávio Manoel Rodrigues da SilvaJr Ana Luiza Muccillo-Baisch Cristiana Lima Dora 《Pharmaceutical research》2016,33(4):983-993
Purpose
This study evaluates the advantage of the quercetin encapsulation in nanosized emulsion (QU-NE) administered orally in rats in order to demonstrate its anti-oedematous and antioxidant effects as well as its toxicity.Methods
The nanocarriers were prepared using the hot solvent diffusion with the phase inversion temperature methods. The nanocarriers physicochemical properties were then investigated. The anti-edematous activity was tested using paw edema in rats. In addition, NF-kB expression in subcutaneous tissue of the paws was accessed by immunohistochemistry while the lipid peroxidation was analyzed in the liver by malondialdehyde reaction with thiobarbituric acid. Hematological, renal and hepatic toxicity as well as the genetic damage were also evaluated.Results
The results demonstrated that QU-NE exhibited pronounced anti-oedematous property comparable to drug diclofenac. This effect was associated with NF-κB pathway inhibition. The lipid peroxidation was also only reduced in rats treated with QU-NE. Besides this, no genetic damage, hematological, renal or hepatic toxicities were observed after administration of QU-NE.Conclusions
These results suggest that quercetin nanosized emulsion exhibits anti-oedematous and antioxidant properties and does not demonstrate toxic effects. This indicates that it has a potential application in the treatment of inflammatory diseases.10.
Soares Rogerio N. Ramirez-Perez Francisco I. Cabral-Amador Francisco J. Morales-Quinones Mariana Foote Christopher A. Ghiarone Thaysa Sharma Neekun Power Gavin Smith James A. Rector R. Scott Martinez-Lemus Luis A. Padilla Jaume Manrique-Acevedo Camila 《Age (Dordrecht, Netherlands)》2022,44(3):1657-1675
GeroScience - Aging of the vasculature is characterized by endothelial dysfunction and arterial stiffening, two key events in the pathogenesis of cardiovascular disease (CVD). Treatment with sodium... 相似文献