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排序方式: 共有609条查询结果,搜索用时 15 毫秒
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Esther Abels Liron Pantanowitz Famke Aeffner Mark D Zarella Jeroen van der Laak Marilyn M Bui Venkata NP Vemuri Anil V Parwani Jeff Gibbs Emmanuel Agosto-Arroyo Andrew H Beck Cleopatra Kozlowski 《The Journal of pathology》2019,249(3):286-294
In this white paper, experts from the Digital Pathology Association (DPA) define terminology and concepts in the emerging field of computational pathology, with a focus on its application to histology images analyzed together with their associated patient data to extract information. This review offers a historical perspective and describes the potential clinical benefits from research and applications in this field, as well as significant obstacles to adoption. Best practices for implementing computational pathology workflows are presented. These include infrastructure considerations, acquisition of training data, quality assessments, as well as regulatory, ethical, and cyber-security concerns. Recommendations are provided for regulators, vendors, and computational pathology practitioners in order to facilitate progress in the field. © 2019 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland. 相似文献
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Journal of Neurology - 相似文献
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Robertson NP; Shaunak S; Compston DA 《QJM : monthly journal of the Association of Physicians》1998,91(4):309-313
We retrospectively analysed patients seen in a rapid referral clinic to
identify those with abnormalities genuinely requiring urgent assessment,
and to evaluate the impact of the clinic on routine services. After
advertising the availability of the service, 25% of telephone referrals
from primary-care physicians led to identification of patients considered
suitable for urgent evaluation. We assessed 350 patients over an 18-month
period. After neurological review, relevant abnormalities were identified
in 73%, and 33% were considered to have warranted urgent assessment. In
addition, 74% required radiological evaluation and 14% had a
neurophysiological procedure; 19.4% were admitted on the same day, 13%
underwent CSF analysis and 34% required some form of therapeutic
intervention. In retrospect, patients with a clinical history of > 11
days rarely warranted urgent referral. Visual failure and diplopia provided
the highest correlation with patients deemed to require urgent assessment,
and syncope and headache the lowest. Despite the number of patients
reviewed, no effect was demonstrated on waiting times for standard
out-patient review.
相似文献
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Chalmers RM; Howard RS; Wiles CM; Hirsch NP; Miller DH; Williams A; Spencer GT 《QJM : monthly journal of the Association of Physicians》1996,89(6):469-476
Twenty-nine patients with a neuronopathic or neuropathic disorder were
referred for assessment of respiratory insufficiency between 1978 and 1994.
Diagnoses included spinal muscular atrophy (6), chronic idiopathic
demyelinating neuropathy (4), Vialetto-van Laere syndrome (3), hereditary
motor and sensory neuropathy (3) and a miscellaneous group (5). We also
describe seven patients with Guillain-Barre syndrome (GBS) who required
long-term ventilatory support for over 6 months to 7 years after the
initial illness. Respiratory insufficiency occurred as a consequence of
respiratory muscle weakness, impaired bulbar function and restrictive lung
defects. In some groups presentation was with progressive nocturnal
hypoventilation culminating in acute respiratory failure. Five patients
with GBS or chronic idiopathic demyelinating neuropathy were weaned from
ventilatory support up to 18 months after the initial illness. The
remaining 24 patients required continuous or nocturnal ventilatory support
using intermittent positive-pressure ventilation (13), negative pressure
ventilation (4), nasal-mask-delivered intermittent positive-pressure
ventilation (4), nasal-mask-delivered continuous positive-pressure
ventilation (3), mouthpiece-assisted ventilation by day (2) and rocking bed
(1). None have been weaned from support after a period of ventilation
ranging from one month to 10 years. Eight patients have subsequently died.
相似文献
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Longitudinal study of the substantia nigra in Parkinson disease: A high‐field 1H‐MR spectroscopy imaging study 下载免费PDF全文
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Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor‐risk metastatic renal cell carcinoma 下载免费PDF全文