Survey on changes in subjective symptoms,onset/trigger factors,allergic diseases,and chemical exposures in the past decade of Japanese patients with multiple chemical sensitivity

Background

Recently, with rapid changes in the Japanese lifestyle, the clinical condition of patients with multiple chemical sensitivity (MCS) may also have undergone change. Thus, we conducted a new survey for subjective symptoms, ongoing chemical exposures, the prevalence of allergic diseases, and presumed onset/trigger factors in patients with MCS and compared results with those of an old survey from ten years ago.

Mucocele of the glands of Blandin-Nuhn: clinical and histopathologic analysis of 26 cases

We investigated the clinical and histopathologic features of 26 cases of mucocele of the glands of Blandin-Nuhn. There was a female predominance, and most patients were younger than 20 years. Fifteen patients first visited a medical doctor and 9 visited a dentist before being referred to our department. The average duration from the time the lesion was first noticed to the patient's visit was 3.6 months. All lesions were located on the ventral surface of the tongue. In 17 patients, mucoceles were seen at the tip of the tongue, whereas 9 lesions occurred more posteriorly. Lesions were situated at the midline in 19 patients and laterally in 7 patients. All lesions presented as an exophytic mass, often with a polypoid appearance. All mucoceles were histopathologically of the extravasation type, suggesting that trauma may represent a frequent initiating factor.     

Color compatibility of resin composites of identical shade designation.

OBJECTIVE: The aim of this study was to evaluate color compatibility of corresponding resin composite shades keyed to Vitapan Classical shade guide (Vita). METHOD AND MATERIALS: Twenty-one shades of 6 commercial resin composites were analyzed. Specimens (n = 5) were made as disks, 11 mm in diameter and 2 mm thick, using cylindrical molds. Specimens were polymerized according to manufacturers' suggestions using a light-curing unit. Data were collected using a spectrophotometer and analyzed using the appropriate color difference metric equations. A total color difference (deltaE*ab) greater than or equal to 3.7 was considered a mismatch. Analysis of variance and Fisher's probable least-squares difference (PLSD) test. intervals for comparison of means were calculated at the .05 level of significance. RESULTS: Mean deltaE*ab values among A2, B2, C2, and opaque A2 shade pairs were 4.4 (1.8), 7.3 (3.2), 5.6 (2.8), and 6.5 (1.8), respectively, while the mean color difference for all the pairs compared was 5.8 (2.8). For A2 shades, deltaL*, deltaa*ab, and deltab*ab values ranged by 5.3, 2.3, and 6.7, respectively. Corresponding values for B2 shades ranged by 10.5, 2.2, and 11.5; 7.9, 2.2, and 4.3 for C2 shades; and 7.9, 1.4, and 4.4 for opaque A2 shades. Fisher's PLSD critical intervals for comparing deltaE*ab values among the shades and composite pairs were 0.07 and 0.15, respectively (P < .0001, power 1.00). CONCLUSION: Overall, poor color compatibility of shade pairs of identical shade designation was recorded. The best color match was recorded for A2 shade pairs, followed by C2, B2, and opaque A2 shade pairs.     

Usefulness of CT images for diagnosis of odontogenic maxillary sinusitis

To assess the usefulness of CT images for the diagnosis of suspected odontogenic maxillary sinusitis, 52 patients with maxillary sinusitis who had received CT examination were retrospectively analyzed. maxillary sinus ostium was established on coronal CT image in 20 out of 55 lesions in those 52 patients. However, a considerable number of patients who had inflammatory disease not only in the maxillary sinus but also in other paranasal sinuses (38/55) or in the nasal meatus (34/55) were included in those 52 patients. Concerning the opening of the ostium, the clinical diagnosis is frequently different from the diagnosis made using CT. The CT findings of the maxillary sinus ostium, nasal meatus and other paranasal sinuses were thus important in planning the treatment for patients with maxillary sinusitis in dentistry, as in otorhinolaryngology.     

Coverage of gingival recession defects using guided tissue regeneration with and without adjunctive enamel matrix derivative in a dog model

The aim of this study was to clarify the adjunctive effect of enamel matrix derivative (EMD) on expanded polytetrafluoroethylene membrane guided tissue regeneration (GTR)-based root coverage by creating gingival recessions in beagle dogs. Recessions were treated with GTR + EMD, GTR alone, or neither GTR nor EMD (control). The control group was characterized by long junctional epithelium and little bone formation. The GTR + EMD group showed a statistically significant increase (P < .01) in new bone and cementum formation compared with the GTR group. The results of the present investigation suggest that the adjunctive use of EMD with GTR promotes formation of new bone and cementum without root resorption in recession-type defects in dogs.     

Changes in cerebral blood flow during steady-state cycling exercise: a study using oxygen-15-labeled water with PET

Cerebral blood flow (CBF) during dynamic exercise has never been examined quantitatively using positron emission tomography (PET). This study investigated changes in CBF that occur over the course of a moderate, steady-state cycling exercise. Global and regional CBF (gCBF and rCBF, respectively) were measured using oxygen-15-labeled water (H₂¹⁵O) and PET in 10 healthy human subjects at rest (Rest), at the onset of exercise (Ex1) and at a later phase in the exercise (Ex2). At Ex1, gCBF was significantly (P<0.01) higher (27.9%) than at Rest, and rCBF was significantly higher than at Rest in the sensorimotor cortex for the bilateral legs (M1_Leg and S1_Leg), supplementary motor area (SMA), cerebellar vermis, cerebellar hemispheres, and left insular cortex, with relative increases ranging from 37.6% to 70.5%. At Ex2, gCBF did not differ from Rest, and rCBF was significantly higher (25.9% to 39.7%) than at Rest in only the M1_Leg, S1_Leg, and vermis. The areas showing increased rCBF at Ex1 were consistent with the central command network and the anatomic pathway for interoceptive stimuli. Our results suggest that CBF increases at Ex1 in parallel with cardiovascular responses then recovers to the resting level as the steady-state exercise continues.