全文获取类型
收费全文 | 2946篇 |
免费 | 165篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 27篇 |
儿科学 | 79篇 |
妇产科学 | 63篇 |
基础医学 | 330篇 |
口腔科学 | 49篇 |
临床医学 | 309篇 |
内科学 | 771篇 |
皮肤病学 | 56篇 |
神经病学 | 338篇 |
特种医学 | 72篇 |
外科学 | 327篇 |
综合类 | 17篇 |
一般理论 | 2篇 |
预防医学 | 148篇 |
眼科学 | 44篇 |
药学 | 174篇 |
中国医学 | 12篇 |
肿瘤学 | 307篇 |
出版年
2023年 | 21篇 |
2022年 | 13篇 |
2021年 | 47篇 |
2020年 | 37篇 |
2019年 | 49篇 |
2018年 | 70篇 |
2017年 | 54篇 |
2016年 | 60篇 |
2015年 | 54篇 |
2014年 | 80篇 |
2013年 | 115篇 |
2012年 | 162篇 |
2011年 | 168篇 |
2010年 | 80篇 |
2009年 | 88篇 |
2008年 | 172篇 |
2007年 | 173篇 |
2006年 | 172篇 |
2005年 | 133篇 |
2004年 | 123篇 |
2003年 | 125篇 |
2002年 | 111篇 |
2001年 | 111篇 |
2000年 | 111篇 |
1999年 | 89篇 |
1998年 | 34篇 |
1997年 | 38篇 |
1996年 | 21篇 |
1995年 | 29篇 |
1994年 | 29篇 |
1993年 | 21篇 |
1992年 | 49篇 |
1991年 | 52篇 |
1990年 | 43篇 |
1989年 | 42篇 |
1988年 | 56篇 |
1987年 | 39篇 |
1986年 | 31篇 |
1985年 | 22篇 |
1984年 | 21篇 |
1983年 | 14篇 |
1982年 | 10篇 |
1981年 | 8篇 |
1979年 | 28篇 |
1978年 | 12篇 |
1977年 | 9篇 |
1974年 | 11篇 |
1972年 | 8篇 |
1969年 | 14篇 |
1967年 | 7篇 |
排序方式: 共有3125条查询结果,搜索用时 31 毫秒
1.
Nancy E Leone 《Gastroenterology nursing》2002,25(5):201-203
The treatment for chronic hepatitis C with interferon and ribavirin is associated with a large number of untoward side effects ( Cornberg, Wedemeyer &, Manns, 2002). Management of these adverse effects has a great impact on the compliance of affected patients during the course of their treatment. Thus, the influence of the nurse on patient compliance and quality of life improvement during interferon and ribavirin treatment cannot be understated. Anecdotally, from the patient's point of view, the adverse effects of treatment often overshadow the goal of treatment, viral clearance. Nurses, as a result of their role as patient advocates, have the ability to enhance treatment compliance greatly by recognizing and managing treatment-associated side effects. 相似文献
2.
Lycopene, a non-provitaminic carotenoid, present in many fruit and vegetables, such as tomatoes and their processed products, has been associated with decreased risk of chronic diseases including cancer. The influence of lycopene on the proliferation of the breast tumour cell line (MCF-7) was tested using MTT and BrdU assays at different time intervals (from 24 to 72h) and dose-response (from 0.125 to 100muM). The induction of Gap Junction Intercellular Communication (GJIC) was evaluated by dye-transfer assay using Lucifer Yellow on monolayer cells treated with different lycopene concentrations (from 0.125 to 5muM) for 6 to 48h. The Minimal Inhibitory Concentration (MIC) of lycopene was of 5muM, after a 24h exposure. A prolonged exposure time (72h) induced a similar inhibitory effect. Lycopene stimulated the functionality of GJIC at concentrations of 1muM after 24h and this effect was dose-dependent. The induction of GJIC by lycopene was confirmed by an increased expression of connexin 43. Collectively, the above data confirm the inhibitor effects of lycopene on MCF-7 cell growth and suggest that lycopene is involved in the modulation of the gap junction intercellular communication in this cell line, as observed for other cancer cell lines. 相似文献
3.
Abstract: Research indicates that two major forms of partner violence exist, intimate terrorism (IT) and situational couple violence (SCV). The current study (N= 389) used a subgroup of women who responded to the Chicago Women’s Health Risk Study to examine whether type of violence experienced is differentially related to formal (e.g., police, medical agencies, counseling) and informal (e.g., family, friends/neighbors) help seeking. IT victims were more likely to seek each type of formal help but were equally or less likely to seek informal help. Findings can inform both family violence research and the development and implementation of social service programs. 相似文献
4.
J W Shore C T Westfall C R Leone R K Newman F W Shagets 《Ophthalmic plastic and reconstructive surgery》1987,3(1):13-15
A 38-year-old man presented with hyperophthalmia, enophthalmos, and upper eyelid retraction 18 months following an osteoplastic flap and frontal sinus obliteration for mucocele. Computerized tomography confirmed the presence of frontal bone absorption in the roof of the orbit with traction and elevation of the orbital contents into the obliterated frontal sinus. A fracture of the orbital roof with penetration of periorbita at the time of original surgery was the suspected precipitating cause of the complication. Surgical management included lysis of the cicatrix between the orbit and frontal sinus and interposition of a silicone sheet between the orbit and sinus, which restored the appropriate anatomic relationships and prevented recurrence. 相似文献
5.
Paolo Ammendola Adolfo Zambelli Leone Oliva Teodorico Tancredi 《Macromolecular chemistry and physics.》1986,187(5):1175-1188
The chain propagation rate constants for the polymerization of ethylene and propene in the presence of δ-TiCl3/Al(CH3)3 at 22 °C are determined by means of a 13C NMR analysis of suitable block copolymers. The numerical values of the rate constants are compared with those previously reported. 相似文献
6.
Andrea Gallamini Alberto Biggi Adriana Fruttero Francesco Pugno Giobatta Cavallero Patrizia Pregno Mariella Grasso Chiara Farinelli Alessandro Leone Eugenio Gallo 《European journal of nuclear medicine and molecular imaging》1997,24(12):1499-1506
The purpose of this study was threefold: to evaluate the role of gallium-67 scintigraphy in the staging of low-grade non-Hodgkin’s
lymphomas (LGNHL), to assess the relationship between the expression of CD71 on the surface of the neoplastic cells and the
67Ga uptake by the tumour, and to establish the contribution of 67Ga scan in defining the prognosis of LGNHL. Forty-eight patients with untreated LGNHL diagnosed in a single institution over
a decade were reviewed. The end point of the study was survival of the patients according to the scintigraphic 67Ga score at diagnosis. In addition to 67Ga scan, other prognostic variables were studied, relating to the neoplastic burden, the biology of the tumour and the host.
Univariate and multivariate analyses were used. 67Ga scan identified only 116/286 (41%) nodes involved by lymphoma that were detected by clinical examination or computed tomography
scan. A scintigraphic scoring system with an arbitrary cut-off value of 3 (high scan score) was able to predict patients with
a dismal prognosis: with a mean follow-up of 47 months (range: 1–146 months) the median survival time was 28 months in patients
with a high scan score and 74 months in patients with a low scan score (P=0.002). CD71 values were 27.4%±14.9% (mean ±SD) in the former and 8.9%±7.2% in the latter (P=0.0001). Only performance status and extranodal sites were significant variables for prognosis in multivariate analysis.
It is concluded that 67Ga scan is inaccurate in staging but might be very important in defining the prognosis in LGNHL, in association with other
prognostic variables.
Received 1 May and in revised form 6 August 1997 相似文献
7.
Antonio C Pastorino Rejane D C Rimazza Cláudio Leone Ana Paula M Castro Dirceu Solé Cristina M A Jacob 《The Journal of asthma》2006,43(9):695-700
BACKGROUND: Identify risk factors for asthma in adolescents from S?o Paulo, Brazil. METHODS: total of 528 adolescents (141 asthmatics, 387 control subjects) from the ISAAC study (phase III) were submitted to a complementary questionnaire to evaluate risk factors, through response to questions regarding personal history, environment, and diet and an agreement to undergo the skin prick test (SPT) for aeroallergens. RESULTS: Positive SPT to at least one allergen occurred in 49.4% adolescents. The risk factors for asthma were: prematurity (OR: 3.84, 95% CI: 1.54-9.64), rhinitis (OR: 3.18, 95% CI: 1.71-5.91), positivity in the SPT (OR: 2.81, 95% CI: 1.48-5.32), eczema in characteristic skin-folds (OR: 2.86, 95% CI: 1.13-7.26), and an allergic mother (OR: 2.01, 95% CI: 1.02-3.93). The consumption of cooked vegetables was a protective factor for asthma (OR: 0.37, 95% CI: 0.18-0.79) CONCLUSIONS: Asthma is a multifatorial disease. An allergic mother, aeroallergen sensitization, rhinitis, eczema and prematurity were considered risk factors and the consumption of cooked vegetables was considered a protective factor for asthma in this population. 相似文献
8.
9.
10.
Support vector machines (SVMs) are a powerful technique developed in the last decade to effectively tackle classification and regression problems. In this paper we describe how support vector machines and artificial neural networks can be integrated in order to classify objects correctly. This technique has been successfully applied to the problem of determining the quality of tiles. Using an optical reader system, some features are automatically extracted, then a subset of the features is determined and the tiles are classified based on this subset. 相似文献