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Adam R. Cassidy Jane Holmes Bernstein David C. Bellinger Jane W. Newburger David R. DeMaso 《The Clinical neuropsychologist》2019,33(4):760-778
Objective: To determine whether visual-spatial processing style is associated with psychopathology in a large sample of adolescents with critical congenital heart disease (CHD). Local (part-oriented) style was hypothesized to increase risk for internalizing (but not externalizing) forms of psychopathology.Method: Participants included 278 adolescents with critical CHD (dextro-transposition of the great arteries?=?134, tetralogy of Fallot?=?58, single-ventricle cardiac anatomy requiring the Fontan procedure?=?86). Visual-spatial processing style was indexed using Copy Style Ratings from the Rey-Osterrieth Complex Figure-Developmental Scoring System. The Schedule for Affective Disorders and Schizophrenia for School-Aged Children–Present & Lifetime Version was used to determine presence/absence of diagnosable DSM-IV psychiatric disorder(s). Processing style and psychopathology were assessed concurrently.Results: Thirty-three percent of the sample had a part-oriented processing style. In multivariable binary logistic regression models, part-orientation was associated with more than twice the odds of having an anxiety disorder (lifetime: OR?=?2.2, p?=?.02, 95% CI?=?1.1–4.1; current: OR?=?2.7, p?=?.03, 95% CI?=?1.1–6.5) but was not associated with an increased risk for ADHD, disruptive behavior, or mood disorders (ps?>?.05).Conclusions: Adolescents with critical CHD who approach complex visual-spatial materials in a local, part-oriented fashion are more likely to meet criteria for an anxiety disorder than those who approach complexity more holistically. Part-orientation may make it more difficult for individuals to judge the relative importance of isolated details and engage in more adaptive perspective-taking. 相似文献
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Natasha Robinson-Link Sharon Hoover Larraine Bernstein Nancy Lever Kenneth Maton Holly Wilcox 《School mental health》2020,12(2):239-249
While schools have the capacity to reach youth at-risk for suicide, there remains a gap between the number of youth with mental health issues and those who 相似文献
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Ido Tavor Rotem Botvinik‐Nezer Michal Bernstein‐Eliav Galia Tsarfaty Yaniv Assaf 《Human brain mapping》2020,41(2):442-452
Current noninvasive methods to detect structural plasticity in humans are mainly used to study long‐term changes. Diffusion magnetic resonance imaging (MRI) was recently proposed as a novel approach to reveal gray matter changes following spatial navigation learning and object‐location memory tasks. In the present work, we used diffusion MRI to investigate the short‐term neuroplasticity that accompanies motor sequence learning. Following a 45‐min training session in which participants learned to accurately play a short sequence on a piano keyboard, changes in diffusion properties were revealed mainly in motor system regions such as the premotor cortex and cerebellum. In a second learning session taking place immediately afterward, feedback was given on the timing of key pressing instead of accuracy, while participants continued to learn. This second session induced a different plasticity pattern, demonstrating the dynamic nature of learning‐induced plasticity, formerly thought to require months of training in order to be detectable. These results provide us with an important reminder that the brain is an extremely dynamic structure. Furthermore, diffusion MRI offers a novel measure to follow tissue plasticity particularly over short timescales, allowing new insights into the dynamics of structural brain plasticity. 相似文献
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Edward Fletcher Alan Askari Yunfei Yang Samuel Adegbola Yasser Al‐Obudi Darryl Bernstein Krasha Patel Amit Gupta Omar Abbasi Hasna Anda Harjot Birdi Mohammed Rabie Shahla Siddique Hesham El‐Hakim Chelise Currow Alice Rudge Mohamed Aly Paul Cathcart Stephen Crockett Michael Ha Medhat Aker Ketan Dhatariya 《International journal of clinical practice》2020,74(4)
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Seungmi Ryu Nicola Martino Sheldon J. J. Kwok Liane Bernstein Seok-Hyun Yun 《Biomedical optics express》2021,12(3):1437
Brillouin light scattering offers a unique label-free approach to measure biomechanical properties non-invasively. While this technique is used in biomechanical analysis of cells and tissues, its potential for visualizing structural features of tissues based on the biomechanical contrast has not been much exploited. Here, we present high-resolution Brillouin microscopy images of four basic tissue types: muscular, connective, epithelial, and nervous tissues. The Brillouin contrast distinguishes between muscle fiber cells and endomysium in skeletal muscle and reveals chondrocytes along with spatially varying stiffness of the extracellular matrix in articular cartilage. The hydration-sensitive contrast can visualize the stratum corneum, epidermis, and dermis in the skin epithelium. In brain tissues, the Brillouin images show the mechanical heterogeneity across the cortex and deeper regions. This work demonstrates the versatility of using the Brillouin shift as histological contrast for examining intact tissue substructures via longitudinal modulus without the need for laborious tissue processing steps. 相似文献
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