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1.
Lucena Rita de Melo-Carneiro Pedro Sampaio Aline Santos de Almeida Nadia Rossi Ponte Ana Marta Vieira de Brito Wanderley Daniele de Mattos Adriana Marques Robatto Ana Paola Argollo Nayara 《Journal of autism and developmental disorders》2022,52(9):4202-4203
Journal of Autism and Developmental Disorders - 相似文献
2.
Dominic Kaddu-Mulindwa Sophie Roth Aline Klees-Rollmann Klaus Fassbender Mathias Fousse 《Journal of neurovirology》2020,26(2):292-296
The development of anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is often associated with neoplasia or infectious diseases as antibodies against neurons or synaptic proteins surface. A 30-year-old male patient was admitted to our department because of neurocognitive symptoms, particularly memory difficulties which had appeared a year prior and since then had been increasing. He had a medical history of smoking and hypertension. On examination, there were no focal neurological deficits. However, neuropsychological tests confirmed a lack of concentration and short-term memory impairment. Brain magnetic resonance imaging (MRI) and electroencephalography (EEG) remained unremarkable. Cerebrospinal fluid (CSF) analysis revealed a low lymphocytic pleocytosis without oligoclonal bands. Serum testing for human immunodeficiency virus (HIV) was positive with 420,000 HIV-1-RNA copies/ml. On a more detailed physical examination, a large number of purple patches were found on the entire body, which a biopsy confirmed to be Kaposi sarcoma (KS). A positive serum and CSF NMDA receptor antibody titer (serum 1:280; CSF 1:8) confirmed the diagnosis of an AIDS-associated anti-NMDA receptor encephalitis; therefore, we treated him with antiretroviral and immunosuppressive therapy. After 12 months, the KS lesions faded and the cognitive deficits improved slightly. Our case highlights that a detailed clinical examination and searching for neoplasia and/or an infection are helpful, though often neglected, tools for detecting an anti-NMDA receptor encephalitis. 相似文献
3.
Doreen A. Ezeife MD Francois Dionne PhD Aline Fusco Fares MD Ellen Laura Rose Cusano MD Rouhi Fazelzad BSc MISt Wenzie Ng BSc MPharm RPh Don Husereau BSc Pharm MSc Farzad Ali BPharm MSc Christina Sit MSc Barry Stein B.Com BCL LLB Jennifer H. Law MSc Lisa Le MSc Peter Michael Ellis MD MMed PhD Scott Berry MD Stuart Peacock PhD Craig Mitton PhD Craig C. Earle MD Kelvin K. W. Chan MD PhD Natasha B. Leighl MD MMSc 《Cancer》2020,126(7):1530-1540
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Chaves Aline Lauda Freitas Silva Ana Gabriela Maia Flávia Medeiros Lopes Gabriela Francine Martins de Paulo Luiz Fernando Barbosa Muniz Luciana Vieira dos Santos Hélio Batista Soares João Marcos Arantes Souza Alexandre Andrade de Oliveira Barbosa Leandro Augusto Loyola Adriano Mota Murta Eddie Fernando Candido Michelin Márcia Antoniaze de Azambuja Ribeiro Rosy Iara Maciel 《Clinical oral investigations》2019,23(4):1913-1919
Clinical Oral Investigations - The aim of this study was to evaluate the immunohistochemical expressions of PD1, CD4+, and CD8+ in premalignant lesions (OPML) that were transformed into oral... 相似文献
7.
Rhea Farhat Jennifer Assaf Hicham Jabbour Hady Licha Aline Hajj Souheil Hallit Lydia Rabbaa Khabbaz 《Saudi Pharmaceutical Journal》2019,27(1):126-132
Objective
To evaluate treatment adherence to oral glucose lowering drugs (OGLD) and health related quality of life in Lebanese diabetics. Secondary objectives were to examine associations between treatment adherence, quality of life (QOL), treatment satisfaction and illness perception.Methods
This cross-sectional study, conducted in all districts of Lebanon between August 2016 and April 2017, enrolled 207 adult patients, taking any OGLD.Results
The effectiveness score (Beta?=?0.55), female gender (Beta?=?7.04), and the quality of life score (Beta?=?0.28) would significantly increase the adherence score respectively. On another hand, the body mass index (Beta?=??1.216) would significantly decrease the adherence score. Adherence was negatively and significantly associated to IPQ score (r?=??0.181), effectiveness score (r?=??0.504), side effects (r?=??0.583), convenience (r?=??0.317), global satisfaction (r?=??0.428), physical health (r?=??0.477), psychological health (r?=??0.521), social relationships (r?=??0.405) and environment (r?=??0.429).Conclusion
Perceived effectiveness and patient’s quality of life seem to be important parameters enhancing adherence. Based on this study, planning interventions to enhance treatment adherence and improve the quality of life is crucial for all diabetic patients. Additional efforts are suggested to be made by concerned authorities to set up awareness campaigns to increase alertness on the importance of adherence to medications in diabetics. 相似文献8.
Esteves Georgia Rodrigues Junior Ivaldo Esteves Masson Igor Fagioli Bordello Machado Aline Fernanda Perez Oliveira Maria Carolina Derencio Baldan Cristiano Schiavinato Farcic Thiago Saikali Liebano Richard Eloin Plapler Hélio 《Lasers in medical science》2022,37(3):1495-1501
Lasers in Medical Science - The aim of this study was to investigate the effect of red laser (660 nm) photobiomodulation (PBM) with different energies on tumor necrosis factor-alpha(TNF-α)... 相似文献
9.
John Lennon Silva Cunha Amanda Almeida Leite Thamiris de Castro Abrantes Lorena Passoni Vervloet Thayn Melo de Lima Morais Gerson de Oliveira Paiva Neto Tatiana Nayara Librio Kimura Snia Maria Soares Ferreira Ricardo Luiz Cavalcanti de Albuquerque‐Júnior Aline Corrêa Abraho Mario Jos Romaach Bruno Augusto Benevenuto de Andrade Oslei Paes de Almeida Ciro Dantas Soares 《Journal of cutaneous pathology》2021,48(1):24-33
10.
Claudia R. L. Cardoso Christian N. Roderjan Aline H. Cavalcanti Arthur F. Cortez Elizabeth S. Muxfeldt Gil F. Salles 《Journal of sleep research》2020,29(4)
Resistant hypertension (RHT) is associated with obstructive sleep apnea (OSA) and increased aortic stiffness, measured by carotid‐femoral pulse wave velocity (cf‐PWV). We aimed to evaluate in a randomized controlled trial, the effect of Continuous positive airway pressure (CPAP) treatment on cf‐PWV in comparison with a control group in patients with RHT and moderate‐severe OSA. One‐hundred and sixteen patients were randomized to 6‐month CPAP treatment (56 patients) or no therapy (60 patients), while keeping their antihypertensive treatment unchanged. Carotid‐femoral pulse wave velocity was performed at the beginning and end of the 6‐month period. Intention‐to‐treat intergroup differences in cf‐PWV changes were assessed by a generalized mixed‐effects model with the allocation group as a fixed factor and adjusted for age, sex, changes in mean arterial pressure and the baseline cf‐PWV values. Subgroup sensitivity analyses were performed, excluding patients with low CPAP adherence and low cf‐PWV at baseline. CPAP and control groups had similar clinic‐laboratorial characteristics. Patients had a mean cf‐PWV of 9.4 ± 1.6 m/s and 33% presented cf‐PWV > 10 m/s. During treatment, the control group had a mean increase in cf‐PWV of +0.43 m/s (95% confidence interval [CI], +0.14 to +0.73 m/s; p = .005), whereas the CPAP group had a mean increase of +0.03 m/s (95% CI, ?0.33 to +0.39 m/s; p = .87), resulting in a mean difference in changes between CPAP and control of ?0.40 m/s (95% CI, ?0.82 to +0.02 m/s; p = .059). Subgroup analyses did not change the results. In conclusion, a 6‐month CPAP treatment did not reduce aortic stiffness, measured by cf‐PWV, in patients with RHT and moderate/severe OSA, but treatment may prevent its progression, in contrast to no‐CPAP therapy. 相似文献