全文获取类型
收费全文 | 98095篇 |
免费 | 7089篇 |
国内免费 | 318篇 |
专业分类
耳鼻咽喉 | 1290篇 |
儿科学 | 2517篇 |
妇产科学 | 2324篇 |
基础医学 | 12032篇 |
口腔科学 | 2057篇 |
临床医学 | 9642篇 |
内科学 | 21182篇 |
皮肤病学 | 1065篇 |
神经病学 | 8485篇 |
特种医学 | 3364篇 |
外国民族医学 | 3篇 |
外科学 | 16151篇 |
综合类 | 1403篇 |
现状与发展 | 1篇 |
一般理论 | 75篇 |
预防医学 | 7760篇 |
眼科学 | 2641篇 |
药学 | 6332篇 |
中国医学 | 148篇 |
肿瘤学 | 7030篇 |
出版年
2023年 | 368篇 |
2021年 | 1510篇 |
2020年 | 891篇 |
2019年 | 1596篇 |
2018年 | 1912篇 |
2017年 | 1409篇 |
2016年 | 1564篇 |
2015年 | 1847篇 |
2014年 | 2748篇 |
2013年 | 4337篇 |
2012年 | 6215篇 |
2011年 | 6488篇 |
2010年 | 3632篇 |
2009年 | 3345篇 |
2008年 | 6143篇 |
2007年 | 6827篇 |
2006年 | 6529篇 |
2005年 | 6674篇 |
2004年 | 6508篇 |
2003年 | 6125篇 |
2002年 | 6080篇 |
2001年 | 762篇 |
2000年 | 515篇 |
1999年 | 684篇 |
1998年 | 1070篇 |
1997年 | 923篇 |
1996年 | 758篇 |
1995年 | 933篇 |
1994年 | 812篇 |
1993年 | 717篇 |
1992年 | 541篇 |
1991年 | 505篇 |
1990年 | 434篇 |
1989年 | 449篇 |
1988年 | 424篇 |
1987年 | 440篇 |
1986年 | 432篇 |
1985年 | 488篇 |
1984年 | 687篇 |
1983年 | 736篇 |
1982年 | 950篇 |
1981年 | 892篇 |
1980年 | 853篇 |
1979年 | 440篇 |
1978年 | 518篇 |
1977年 | 564篇 |
1976年 | 479篇 |
1975年 | 407篇 |
1974年 | 334篇 |
1973年 | 328篇 |
排序方式: 共有10000条查询结果,搜索用时 133 毫秒
1.
2.
3.
4.
Rates of delivery by caesarean section (CS) are increasing around the globe and, although several epidemiological associations have already been observed between CS and health outcomes in later life, more are sure to be discovered as this practice continues to gain popularity. The components of vaginal delivery that protect offspring from the negative consequences of CS delivery in later life are currently unknown, although much attention to date has focused on differences in microbial colonisation. Here, we present the case that differing hormonal experiences at birth may also contribute to the neurodevelopmental consequences of CS delivery. Levels of each of the ‘birth signalling hormones’ (oxytocin, arginine vasopressin, epinephrine, norepinephrine and the glucocorticoids) are lower following CS compared to vaginal delivery, and there is substantial evidence for each that manipulations in early life results in long‐term neurodevelopmental consequences. We draw from the research traditions of neuroendocrinology and developmental psychobiology to suggest that the perinatal period is a sensitive period, during which hormones achieve organisational effects. Furthermore, there is much to be learned from research on developmental programming by early‐life stress that may inform research on CS, as a result of shared neuroendocrine mechanisms at work. We compare and contrast the effects of early‐life stress with those of CS delivery and propose new avenues of research based on the links between the two bodies of literature. The research conducted to date suggests that the differences in hormone signalling seen in CS neonates may produce long‐term neurodevelopmental consequences. 相似文献
5.
6.
Marc Evans MD Susanne Engberg MD Mads Faurby MSc João Diogo Da Rocha Fernandes MSc Pollyanna Hudson MSc William Polonsky PhD 《Diabetes, obesity & metabolism》2022,24(3):377-390
We designed a systematic literature review to identify available evidence on adherence to and persistence with antidiabetic medication in people with type 2 diabetes (T2D). Electronic screening and congress searches identified real-world noninterventional studies (published between 2010 and October 2020) reporting estimates of adherence to and persistence with antidiabetic medication in adults with T2D, and associations with glycaemic control, microvascular and/or macrovascular complications, hospitalizations and healthcare costs. Ninety-two relevant studies were identified, the majority of which were retrospective and reported US data. The proportions of patients considered adherent (median [range] 51.2% [9.4%-84.3%]) or persistent (median [range] 47.7% [16.9%-94.0%]) varied widely across studies. Multiple studies reported an association between greater adherence/persistence and greater reductions in glycated haemoglobin levels. Better adherence/persistence was associated with fewer microvascular and/or macrovascular outcomes, although there was little consistency across studies in terms of which outcomes were improved. More adherent and more persistent patients were typically less likely to be hospitalized or to have emergency department visits/admissions and spent fewer days in hospital annually than less adherent/persistent patients. Greater adherence and persistence were generally associated with lower hospitalization costs, higher pharmacy costs and lower or budget-neutral total healthcare costs compared with lower adherence/persistence. In conclusion, better adherence and persistence in people with T2D is associated with lower rates of microvascular and/or macrovascular outcomes and inpatient hospitalization, and lower or budget-neutral total healthcare expenditure. Education and treatment strategies to address suboptimal adherence and persistence are needed to improve clinical and economic outcomes. 相似文献
7.
8.
9.
10.
Julia H. Vermylen Gordon J. Wood Elaine R. Cohen Jeffrey H. Barsuk William C. McGaghie Diane B. Wayne 《Journal of pain and symptom management》2019,57(3):682-687