丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

目的 观察慢性乙型肝炎患者应用丹参注射液和异甘草酸镁治疗后肝功能和肝纤维化指标的改善情况.方法 将80例慢性乙型肝炎患者,随机分为丹参组40例,异甘草酸镁组40例,在常规保肝治疗基础上,两组分别加用丹参注射液和异甘草酸镁注射液治疗,疗程均为30 d.观察两组患者治疗前、后的肝功能和肝纤维化指标[血清透明质酸酶(HA)、层黏连蛋白(LN)、Ⅳ型胶原(Ⅳ-C)]的变化.结果 治疗后丹参注射液和异甘草酸镁均可明显改善慢性乙型肝炎患者的肝功能,异甘草酸镁组较丹参组为优(P<0.05).丹参组肝纤维化指标较治疗前有下降(P<0.05);异甘草酸镁组肝纤维化指标与治疗前比较差异无统计学意义(P>0.05);两组治疗后的肝纤维化指标比较,差异有统计学意义(P<0.05).结论 丹参注射液改善肝纤维化的疗效优于异甘草酸镁,而异甘草酸镁改善肝功能的疗效优于丹参注射液.     

探索中小城市专科医院发展新模式

(一 )近年来 ,我国城市医院数量逐步增加 ,规模也不断扩大 ,现有的卫生资源供给总量已基本能够满足当前卫生服务需求 ,有的城市已是供大于求 ,一部分卫生机构的资源利用率不高。与此同时 ,在专科医院建设上却没有受到应有的重视 ,发展相对滞后 ,多数专科医院仍然是骨干少、设备差、水平低、发展慢。专科医院特点在于“专” ,它可以按各种需要和专科发展的要求进行分工 ,为临床科研提供丰富的第一手资料 ,为专科技术人员创造深造条件 ,这些都是综合医院难以实现的。专科医院虽然有它的优势 ,但也有其不足之处 :一是医疗技术拓展受到影响。专…     

丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

Objective To observe the change of liver function and liver fibrosis indexes of the chronic hepatitis B patients that were treated by Danshen injection(DI) and magnesium isnglyeyrrhizinate(MI). Methods 80 chronic hepati-tis B patients based on the conventional treatment were randomly divided into D1 group(40 patients) and MI group(40 pa-tients). The two groups were used with DI and MI injection for 30 days respaetively and then,the levels of liver function and serum hepatic fibrosis(HA, LN, Ⅳ -C) were detected and compared before and after treatment. Results Treatment by DI and MI could both improve liver function significantly, the effect of Ml group was better than DI group(P < 0.05). Moreover, in improving serum hepatic fibrosis, the effect of DI group was better than MI group (P < 0.05). Conclusions The efficacy of the improvement to hepatic fibrosis DI is better than MI, while in improvement of liver function MI is superior to DI.     

新医改形势下传染病医院的发展与出路

当前,由于多种客观原因,传染病医院生存与发展陷入困境,通过对传染病医院的运行情况分析,结合新医改,探讨传染病医院的发展与出路。     

丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

Objective To observe the change of liver function and liver fibrosis indexes of the chronic hepatitis B patients that were treated by Danshen injection(DI) and magnesium isnglyeyrrhizinate(MI). Methods 80 chronic hepati-tis B patients based on the conventional treatment were randomly divided into D1 group(40 patients) and MI group(40 pa-tients). The two groups were used with DI and MI injection for 30 days respaetively and then,the levels of liver function and serum hepatic fibrosis(HA, LN, Ⅳ -C) were detected and compared before and after treatment. Results Treatment by DI and MI could both improve liver function significantly, the effect of Ml group was better than DI group(P < 0.05). Moreover, in improving serum hepatic fibrosis, the effect of DI group was better than MI group (P < 0.05). Conclusions The efficacy of the improvement to hepatic fibrosis DI is better than MI, while in improvement of liver function MI is superior to DI.     

医院专学科建设及学科带头人培养的实践探讨

随着我国医药卫生体制改革的深化．公立医院应注重内涵建设．全面提升服务能力。而做精做细做强特色专科,成为打造医院核心竞争力、提高医院品牌效应的关键。作为一所以传染病诊疗为特色的基层医院．我院以提升专科影响力为目标．着力于学科带头人队伍建没,从而带动学科的快速发展．     

TME联合125I粒子植入治疗中下段直肠癌

目的探讨全直肠系膜切除（TME）联合^125I粒子术中植入治疗进展期中下段直肠癌的效果。方法67例中下段直肠癌TME手术根治患者（均为Dukes’B、C期），分成3组：①组：TME手术根治加化疗组24例；②组：TME手术根治加放疗组18例；③组：TME手术根治联合^125I粒子植入组19例。跟踪随访2年内复发率；同时比较②与③组并发症的发生情况。结果3组1．5年内复发率分别为46％、11％和5％；②、⑧组复发率低于①组（x^2=4．291、6．771，P〈0．05），③组复发率与②组相比差异无显著性；但⑧组并发症的发生率（10％）比②组（44％）明显降低（确切概率计算法，P=0．029）。结论TME联合^125II粒子术中植入有助于预防直肠癌术后复发，且并发症的发生率低。     

探索中小城市专科医院建设发展新模式

近年来,随着医疗卫生事业的迅速发展,我国城市医院数量逐步增加,规模也不断增大,现有的卫生资源供给总量已基本能够满足当前经济水平的卫生服务需要及需求,有的城市已是供大于求,一部分卫生机构的资源利用率不高.与此同时,在专科医院建设上却没有受到应有的重视,发展速度相对滞后,多数专科医院仍然是骨干少、设备差、水平低、发展慢.     

丹参注射液与异甘草酸镁抗肝纤维化的临床对比研究

Objective To observe the change of liver function and liver fibrosis indexes of the chronic hepatitis B patients that were treated by Danshen injection(DI) and magnesium isnglyeyrrhizinate(MI). Methods 80 chronic hepati-tis B patients based on the conventional treatment were randomly divided into D1 group(40 patients) and MI group(40 pa-tients). The two groups were used with DI and MI injection for 30 days respaetively and then,the levels of liver function and serum hepatic fibrosis(HA, LN, Ⅳ -C) were detected and compared before and after treatment. Results Treatment by DI and MI could both improve liver function significantly, the effect of Ml group was better than DI group(P < 0.05). Moreover, in improving serum hepatic fibrosis, the effect of DI group was better than MI group (P < 0.05). Conclusions The efficacy of the improvement to hepatic fibrosis DI is better than MI, while in improvement of liver function MI is superior to DI.     

血必净注射液对MODS患者凝血功能的影响

目的 探讨血必净注射液对多器官功能障碍综合征(MODS)患者凝血功能的影响.方法 将92例MODs患者随机分为治疗组和对照组各46例,对照组予常规西医综合治疗,治疗组在常规西医治疗的基础上加用血必净注射液静脉滴注.2组疗程均为7天.分别检测2组患者治疗前及治疗后1、4、7天的凝血酶原时间、凝血酶时间、活化部分凝血活酶时间、纤维蛋白原和血小板计数,以及治疗第4、7天患者APACHEⅡ评分与Marshall评分.结果 治疗后治疗组第4、7天各凝血参值、评分与对照组比较,差异均有统计学意义(P<0.05,P<0.01).结论 血必净注射液对MODS患者凝血功能有保护作用.