Effect of Sanhuang Jiangtang (三黄降糖) Recipe on Insulin Peripheral Resistance in Type ⅡDiabetes Mellitus

UsingSanhuangJiangtangrecipe(=$@,SHJT,thesameasmodifiedPeachKernalChengqidecoction)intreatingtypefidiabetesmellitus(DM)displayedbeneficialclinicalefficacy(').QuiteanumberofpatientstakenSHJToveraprolongedperiodwereobserved,theirseruminsulinlevelgraduallyloweredslightly,whilebloodsugarloweringstillexisted,whichindicatedthebloodsugarloweringeffectpossiblywasrelatedtotheimprovementofinsulinresistance.Theinsulinresistanceistheprominantcharacteristicsoftype11DM(2),thepresentstudyusinginsulinpe…     

加味桃核承气汤对Ⅱ型糖尿病大鼠胰岛素抵抗的影响

观察加桃核承气汤对Ⅱ型糖尿病的影响。采用链脲佐菌素和高热量饲料的方法模拟ＮＩＤＤＭ大鼠模型，研究加味桃核承气汤对ＮＩＤＤＭ大鼠肝细胞膜胰岛素介体释放，脂肪细胞葡萄糖氧化和胰岛素敏感性指数的影响。加味桃核承气汤可明显降低空腹血糖、胰岛素、摄食量和饮水量（Ｐ〈０．０５￣０．０１），提高胰岛素敏感性（Ｐ〈０．０５），增加肝细胞膜释放的抑制腺苷酸环化酶活力的胰岛素介体量（Ｐ〈０．０５），提高基础的和胰岛素