患者耐受喉罩或气管导管时七氟烷的麻醉深度

Objective To compare the effects of patient's tolerance to laryngeal mask airway (LMA) and tracheal tube (TT) on the appropriate level of sevoflurane anesthesia.Methods Eighty ASA Ⅰ or Ⅱ patients aged 30-60 yr weighing 50-70 kg undergoing elective thyroid or breast surgery were randomly divided into 2 groups (n=40 each):LMA group and TT group.Anesthesia wag induced with propofol 1.6mg/kg,fentanyl 3μg/kg and recuronium 0.6mg/kg.LMA or tracheal tube was inserted,and the patients were mechanically ventilated.Anesthesia was maintained with inhalation of 1.5%-3.0% sevoflurane and 50% N2O in O2 in group LMA,and with 2.5%-5.0% sevoflurane and 50% N2O in O2 in group TT.The flow of O2 and N2O was 0.7-1.0L/min,and the concentration of sevofluranee was adjusted to maintain AAI at 15-25.ECG,HR,MAP,SpO2,PETCO2,AEP and end-tidal sevoflurane concentration were continuonsly monitored.The end-tidal sevoflurane concentration was recorded at 1,5 and 10 min after LMA/TT was placed (T1-3),at 1h after skin incision (T4) and at the end of operation before removal of LMA or extubation (T5).The recovery time of consciousness,adverse cardiovascular events and adverse reactions were recorded.Results The end-tidal sevoflurane concentration was significantly lower,the recovery time of consciousness and removal of LMA or extubation time were shorter,and the incidence of adverse cardiovascular events and adverse reactions was lower in LMA group than in TT group.Conclusion At the same depth of anesthesia (AAI 15-25),sevoflurane concentration is significantly lower in LMA group than in TT group,with fewer complications and smaller cardiovascular reaction.     

盐酸多沙普仑对二种全麻后的催醒效果

盐酸多沙普仑对二种全麻后的催醒效果杨玉欣＊＊颜景佳＊＊李顺元＊＊庄秀琴＊＊柯国辉我院于１９９３年５月至１０月观察应用多沙普仑对两种全麻后病人的催醒效果。一是复方氯胺酮全麻组（氯胺酮１００ｍｇ＋２％利多卡因５ｍｌ＋东莨菪碱０．３ｍｇ，称ＫＬＳ组）２２例...     

麻醉信息系统和数字监测在吸入全麻中的应用

应用麻醉信息管理系统和AEP、MAC等数字监测,比较乳腺手术患者术中吸入七氟醚或异氟醚全麻各自的麻醉效能和术后的苏醒质量,并探讨此类手术的最佳麻醉方案。     

AEP监测下吸入全麻在骨科手术中的应用

骨科手术对肌松和麻醉深度无特别要求,适合应用吸入全麻维持麻醉,但为了减少麻醉过程中对心血管的应激反应和控制适可的麻醉深度,可以选择喉罩气道下的吸入全麻;同时为了更好地掌握控制麻醉深度,麻醉过程中应进行麻醉深度方面的监测.本文旨在观察相同程度的麻醉深度(AAI在18～28之间)下,比较骨科手术中患者经喉罩分别吸入七氟醚或异氟醚全麻过程中各自的特点和术后的苏醒质量,包括苏醒时间、苏醒的完全程度、苏醒期间的并发症情况等进行对比.总结出同样维持在一定范围的麻醉深度(AAI)下七氟醚或异氟醚各自的特点.     

患者耐受喉罩或气管导管时七氟烷的麻醉深度

目的 比较患者耐受喉罩或气管导管时七氟烷的麻醉深度.方法 择期拟行甲状腺手术和乳腺手术的全麻患者80例,ASA Ⅰ或Ⅱ级,年龄30～60岁,体重50～70kg,随机分为2组(n=40):喉罩组(LMA组)和气管导管组(TT组).麻醉诱导:两组均静脉注射异丙酚1.6mg/kg、芬太尼3μg/kg和罗库溴铵0.6mg/kg,插入喉罩或气管导管,行机械通气.麻醉维持:LMA组吸入1.5%～3.0%七氟烷和50%氧化亚氮,TT组吸入2.5%～5.0%七氟烷和50%氧化亚氮.氧气和氧化亚氮的流量均为0.7～1.0 L/min,调节七氟烷吸入浓度,维持听觉诱发电位指数(AAI)15～25.于喉罩或气管导管置入后1min(T1)、5 min(T2)、10 min(T3)、切皮后1h(T4)、术毕拔除喉罩或气管导管前即刻(T5)时记录七氟烷呼气末浓度.记录苏醒时间、心血管不良事件和不良反应的发生情况.结果 与TT组比较,LMA组七氟烷呼气末浓度降低,苏醒时间和拔除喉罩或气管导管的时间缩短,心动过速、苏醒期躁动、咽痛、头晕嗜睡和寒战的发生率降低(P<0.05).结论 在相同的麻醉深度(AAI 15～25)下,患者耐受喉罩比耐受气管导管的七氟烷呼气末浓度降低,并发症少,心血管反应小.     

靶控输注丙泊酚复合瑞芬太尼在40例乳腺手术中的应用

目的探讨靶控输注丙泊酚复合瑞芬太尼在乳腺手术中的麻醉效果。方法选择乳腺手术患者80例,随机分为观察组和对照组。与经喉罩全身麻醉下,对照组进行七氟醚复合氧化亚氮全麻,观察组采用靶控输注丙泊酚复合瑞芬太尼全凭静脉麻醉。记录停用麻醉药即时（T1）、吸痰时（T2）、拔出喉罩时（T3）、拔喉罩后5min（T4）、拔喉罩后10min（T5）等5个时点的AAI、SBP、DBP、HR。记录苏醒时间（停药至唤醒）、拔管时间（停药至拔出喉罩）、苏醒期间不良反应。结果 T4、T52个时点对照组的AAI均小于观察组（P〈0.05）。T2、T3、T43个时点观察组的SBP、DBP和HR值均低于对照组,两组差异有统计学意义（P〈0.05）。结论经喉罩全身麻醉下,丙泊酚复合瑞芬太尼靶控输注全麻比七氟醚复合氧化亚氮全麻后的苏醒效果更为理想。     

经腹腔镜胆囊切除术中呼气末二氧化碳张力的变化

经腹腔镜胆囊切除术时需用二氧化碳气腹以显露手术视野,若二氧化碳被吸收将引起高碳酸血症。作者研究19例经腹腔镜行胆囊切除术病人气腹前后呼气末二氧化碳张力(F_ECO_2)的变化。结果发现麻醉诱导后,注二氧化碳前F_E′CO_2的平均基础值是[(?)(SD)]3.5kPa,在保持通气量不变时,随着二氧化碳注入增多,40分钟后F_E′CO_2达最高值为4.44kPa。若腹腔镜     

七氟烷或丙泊酚联合瑞芬太尼用于全身麻醉的效果比较

目的比较七氟烷复合瑞芬太尼与丙泊酚复合瑞芬太尼两种全身麻醉维持方式在甲状腺手术中的应用效果。方法择期行甲状腺手术的患者60例,随机分为S组和P组各30例。在同样经喉罩全身麻醉并在听觉诱发电位指数（AAI）监测指导下,麻醉维持P组采用靶控输注丙泊酚（靶浓度2．5～3．5mg／L）联合瑞芬太尼（靶浓度4．5-5．5μg/L）效应室靶控输注（TCI）;S组采用吸入七氟烷（2％-4％）联合瑞芬太尼（靶浓度2．5～4．0斗s／L）。记录入室后诱导前（T0）、麻醉诱导后插喉罩前（T1）、插入喉罩时（T2）、切皮时（L3）、游离甲状腺时（T4）、切除甲状腺或肿物时（L5）、拔除喉罩时（T6）和出手术室时（L7）等8个时段的HR、SBP、DBP,停止麻醉至拔除喉罩的时间、拔除喉罩时的清醒程度和术后并发症情况。结果两组HR、SBP、DBP比较,T0、T1、T2、L3等四个时点的差异均无统计学意义（均P〉0,05）;T4、L5、T6、L7等四个时点的差异均有统计学意义（均P〈0．05）。两组问拔除喉罩时间及拔喉罩时清醒程度差异均无统计学意义（均P〉0．05）。术后并发症方面比较,S组苏醒期躁动、头晕嗜睡、寒战和出室时伤口疼痛的发生率较低（均P〈0．05）,两组均未发生恶心呕吐。结论七氟烷复合瑞芬太尼麻醉方式更佳,术中血流动力学更稳定,术后并发症发生率更低。     

患者耐受喉罩或气管导管时七氟烷的麻醉深度

Objective To compare the effects of patient's tolerance to laryngeal mask airway (LMA) and tracheal tube (TT) on the appropriate level of sevoflurane anesthesia.Methods Eighty ASA Ⅰ or Ⅱ patients aged 30-60 yr weighing 50-70 kg undergoing elective thyroid or breast surgery were randomly divided into 2 groups (n=40 each):LMA group and TT group.Anesthesia wag induced with propofol 1.6mg/kg,fentanyl 3μg/kg and recuronium 0.6mg/kg.LMA or tracheal tube was inserted,and the patients were mechanically ventilated.Anesthesia was maintained with inhalation of 1.5%-3.0% sevoflurane and 50% N2O in O2 in group LMA,and with 2.5%-5.0% sevoflurane and 50% N2O in O2 in group TT.The flow of O2 and N2O was 0.7-1.0L/min,and the concentration of sevofluranee was adjusted to maintain AAI at 15-25.ECG,HR,MAP,SpO2,PETCO2,AEP and end-tidal sevoflurane concentration were continuonsly monitored.The end-tidal sevoflurane concentration was recorded at 1,5 and 10 min after LMA/TT was placed (T1-3),at 1h after skin incision (T4) and at the end of operation before removal of LMA or extubation (T5).The recovery time of consciousness,adverse cardiovascular events and adverse reactions were recorded.Results The end-tidal sevoflurane concentration was significantly lower,the recovery time of consciousness and removal of LMA or extubation time were shorter,and the incidence of adverse cardiovascular events and adverse reactions was lower in LMA group than in TT group.Conclusion At the same depth of anesthesia (AAI 15-25),sevoflurane concentration is significantly lower in LMA group than in TT group,with fewer complications and smaller cardiovascular reaction.