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高度近视白内障超声乳化摘除及后房型人工晶体植入术   总被引:24,自引:3,他引:21  
评价高度近视白内障超声乳化摘除及后房型人工晶体植入术的疗效。方法对21例老年性、并发性和先天性白内障施行巩膜隧道切口超声乳化吸除,通过3.2mm切口植入折叠式人工晶体,通过5.5mm切口植入PMMA硬性人工晶体。  相似文献
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目的 比较3种不同长度巩膜隧道外切口超声乳化白内障吸除术后产生手术源性散光(surgically induced astigmatism,SIA)度数及方向的变化规律,并评价手术效果。方法 将104例(104只眼)白内障患者分为A、B、C3组,分别以3.2、5.5及7.0mm巩膜隧道外切口施地超声乳化白内障吸除术,测定术前、术后1周、1、3和6个月的角膜曲率,运用Cravy向量分析法计算SIA度数  相似文献
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目的评价显微玻璃体视网膜手术(microvitreo-retinalsurgery,V-R术)、视网膜切开、硅油填充对穿通伤性视网膜脱离(retinaldetachment,RD)的治疗价值和效果。方法用V-R术结合视网膜切开及硅油填充治疗64例穿通性RD患者。结果出院时视网膜复位者58例(90.6%),其中34例随访3~15个月,视网膜保持平复者占73.5%;视力在数指以上者22只眼(64.7%),≥0.05者6只眼(17.6%)。结论该方法能治愈用常规显微V-R术难以治愈的患者,其中占1/6的患者达到脱盲。  相似文献
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PURPOSE: Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) have been linked to the angiogenic process in general. In order to understand the potential roles of MMP-2, MMP-9 and TIMPs in the corneal neovascularization process, we examined the expression and activities of MMP-2, MMP-9 and TIMPs during the course of cauterization-induced corneal neovascularization in a rat model. METHODS: Neovascularization of rat corneas was induced by silver nitrate cauterization. The expression of MMP-2, MMP-9, TIMP-1 and TIMP-2 was examined by immunohistochemistry and RT-PCR. The protein activities of MMPs and TIMPs were compared in pre- and postcauterization corneas by gelatin zymography and reverse zymography, respectively. RESULTS: MMP-2, TIMP-1 and TIMP-2 immunoreactivities were expressed in normal corneas, predominantly in the corneal epithelium. After injury, immunoreactivities of both MMPs and TIMPs were increased, notably in the healing corneal epithelium, infiltrating inflammatory cells, stromal fibroblasts and ingrowing vascular endothelial cells. The increase in gross MMP-2 enzymatic activity paralleled the maximal vascular ingrowth on day 4, while the gross MMP-9 enzymatic activity rose immediately on day 1, then decreased steadily, which paralleled the magnitude of inflammatory cell infiltration. The immunoreactivity of MMPs/TIMPs decreased significantly 2 weeks after cauterization. On day 35, MMP-2, TIMP-1 and TIMP-2 staining was seen only in corneal epithelium and vascular endothelial cells. Both the RT-PCR and reverse zymography results revealed a more constant expression of TIMP-2, while the TIMP-1 expression appeared to be more inducible. CONCLUSION: MMPs as well as TIMPs were upregulated in cauterization-induced corneal neovascularization, suggesting that both may participate in extracellular matrix remodeling in the corneal wound healing, inflammation and neovascularization processes.  相似文献
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目的 评价弹性开放襻一体型前房型人工晶状体(anter chamber intraocular lens,AC-IOL)植入式的疗效及其安全性。方法 应用超声生物显微镜观察20例(20只眼)弹性开放襻一体型AC-IOL植入术后患者IOL襻的位置,以及其与虹膜及房角结构的关系,从而评价IOL对眼前段结构的影响。随访时间6~20个月。结果 40个IOL襻中,26个襻固定于房角隐窝;14个襻(8只眼)穿过虹膜侵入至睫状体实质内,并伴有反复发作的葡萄膜炎。术后8只眼虹膜前粘连与IOL襻有关。结论 超声生物显微镜检查是动态了解IOL对眼前段结构影响的有效方法。AC-IOL襻的设计有待进一步改进。  相似文献
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外伤性白内障术前B超检查的临床意义   总被引:5,自引:0,他引:5  
目的 探讨外伤性白内障术前采用B超检查后囊破损情况的临床意义。方法 外伤性白内障30只眼,术前采用B超检查评估后囊情况,显微镜下白内障摘除术中直接观察后囊情况并记录。结果 14只眼术前B超检查后囊完整,手术证实12只眼后囊完整,2只眼后囊小破坏。16只眼术前B超检查后囊破损,手术证实14只眼后囊存在大小不等的破损,2只眼后囊完整。结论 外伤性白内障术前B超检查为非侵入性、无痛性检查方法,操作简便,  相似文献
8.
Chen WL  Hu FR  Wang IJ 《Cornea》2001,20(2):141-144
PURPOSE: To determine the leading indications for penetrating keratoplasty and to identify changing trends in these indications during the past 12 years. METHODS: We retrospectively performed a chart review of the hospital records of all patients undergoing penetrating keratoplasty at the National Taiwan University Hospital during a 12-year period (1987-1999). When possible, the clinical indication was corroborated by the pathologic report. RESULTS: A total of 770 corneal transplants were performed. The leading indications for penetrating keratoplasty. in order of decreasing frequency, were corneal scars (27.9%), regraft (21.0%), acute necrotizing and ulcerative keratitis (17.9%), pseudophakic or aphakic bullous keratopathy (17.6%), Fuchs' dystrophy (4.5%), and keratoconus (2.5%). A trend of increasing frequency of regraft and acute necrotizing and ulcerative keratitis, a decreasing frequency of corneal scar, and an initially decreasing then increasing frequency of pseudophakic and aphakic bullous keratopathy were found during the 12-year study period. Acute necrotizing and ulcerative keratitis was found to be the most frequent indication for regraft. CONCLUSION: In this series, corneal scars, regraft, and acute necrotizing and ulcerative keratitis were the leading indications for penetrating keratoplasty. A changing incidence of pseudophakic and aphakic bullous keratopathy noted during the study period was related to the type of intraocular lens implanted and the method of cataract surgery performed. This study found a comparatively high frequency of acute necrotizing and ulcerative keratitis and an extremely low frequency of keratoconus compared with previous reports.  相似文献
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目的用超声生物显微镜观察老年性白内障囊外摘除术及后房型人工晶体植入术后房角的变化及相关因素。方法用超声生物显微镜观察老年性白内障囊外摘除术及后房型人工晶体植入术后,31例(41只眼)的房角改变。结果虹膜周边前粘连6只眼,瞳孔变形12只眼,均与人工晶体襻的位置有关;并非所有非囊袋内固定的人工晶体襻均位于睫状体沟;术后残留的晶体皮质,术后3个月仍存留,较多晶体皮质的残留可引起周边虹膜膨隆、房角变窄。结论后房型人工晶体植入术后房角的改变与人工晶体襻的位置及残留的晶体皮质有关;建议尽可能采用囊袋内植入人工晶体,避免过多的晶体皮质残留。  相似文献
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This study was designed to document and quantify changes in lens clarity over 24 months in a group of diabetic patients. One hundred thirty-four type I and type II diabetics of 3 months' to 45 years' duration with an average age of 53.5 +/- 7 years volunteered to participate in this prospective study. Patients were evaluated upon entry and at 6-month intervals. Scheimpflug lens photographs (Topcon SL45) were taken at each visit. All photographs were evaluated by densitometry which allowed quantification of the light scattering in the various lens layers. A significant and progressive (4-7% every 6 months) increase in light scattering was observed in the lens anterior superficial lens cortex over 24 months. The rate of change in lens clarity was similar in all patients regardless of the clinically observable lens change type (nuclear, cortical, posterior subcapsular, or mixed). Patients who were younger at enrollment, having diabetes of shorter duration and higher glycosylated hemoglobin values (a measure of long-term glucose control), were identified to be at greater risk of having increased densitometry values in the anterior superficial lens cortex. Only a few patients had significant changes in visual acuity during 24 months, and the correlation of superficial cortical lens clarity changes to clinical cataract formation and visual impairment remains to be established.  相似文献
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