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排序方式: 共有10000条查询结果,搜索用时 203 毫秒
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Perkins Jessica M. Kakuhikire Bernard Baguma Charles Rasmussen Justin D. Satinsky Emily N. Kiconco Allen Kananura Justus Audet Carolyn M. Siedner Mark J. Haberer Jessica E. Bangsberg David R. Tsai Alexander C. 《AIDS and behavior》2022,26(6):1892-1904
AIDS and Behavior - Although misperceived norms often drive personal health behaviors, we do not know about this phenomenon in the context of antiretroviral therapy (ART) adherence. We conducted a... 相似文献
3.
Coates Laura C. Mease Philip Kronbergs Andris Helt Cameron Sandoval David Park So Young Combe Bernard Nash Peter Deodhar Atul 《Clinical rheumatology》2022,41(10):3035-3047
Clinical Rheumatology - To evaluate the three-year efficacy and safety of ixekizumab with and without concomitant conventional synthetic disease-modifying antirheumatic drug (csDMARD) use in... 相似文献
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Tudor Kate Maloney Shannon Raja Anam Baer Ruth Blakemore Sarah-Jayne Byford Sarah Crane Catherine Dalgleish Tim De Wilde Katherine Ford Tamsin Greenberg Mark Hinze Verena Lord Liz Radley Lucy Opaleye Emerita Satiro Taylor Laura Ukoumunne Obioha C. Viner Russell Kuyken Willem Montero-Marin Jesus 《Prevention science》2022,23(6):934-953
Prevention Science - There is evidence that universal school-based mindfulness training (SBMT) can have positive effects for young people. However, it is unknown who benefits most from such... 相似文献
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Could Argyrophilic Nucleolar Organizer Regions count mirror DNA Ploidy in Malignant Salivary Gland Tumors? 下载免费PDF全文
Marwa T HussienManar Ali MohamedShima Gafar MansorDoaa F TemerikSherif Farouk ElgayarEnas Alaa El-din Abd El-Aziz 《Asian Pacific journal of cancer prevention》2022,23(6):1983-1992
Objective: Nucleolar organizer regions (NORs) are DNA coils that transcribe to ribosomal RNA. The NOR-associated protein, termed argyrophilic NOR (AgNOR), was visible within the nucleus by staining with silver nitrate examination via the light microscope. AgNOR counting is a proliferation marker and may help in the diagnosis and prognosis of various neoplastic lesions. Aneuploidy (abnormal DNA content) can predict the progression, survival and prognosis of the tumors. The aim of this study was to evaluate the role of AgNORs, DNA ploidy status, and total S-phase fraction (TSPF) as prognostic parameters in malignant salivary gland tumors (MSGTs). Methods: The current study is a retrospective study on a cohort of MSGTs (N=47), to assess AgNORs using Silver Nitrate stain, DNA index (DI), and TSPF using flow cytometry (FCM). Data including tumor size and site, lymphovascular invasion (LVI), lymph node metastasis (LNM) were collected. Results: The AgNORs count was statistically significant with MSGT type. DI was found to have a significant association with tumor site, tumor size and MSGT type. In addition, TSPF was found to be significantly associated with LVI. A moderate positive correlation was noted between AgNORs count and TSPF. LNM, tumor site, high AgNORs and low DI were all associated with short disease-free survival (DFS) and poor overall survival (OS). Conclusion: The present study revealed that high AgNORs count, DNA aneuploidy and TSPF had a poor influence on MSGTs prognosis. 相似文献
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Alicia C. McDonald PhD MPH Jeremy Gernand PhD Nathaniel R. Geyer DrPH Hongke Wu MD MPH Yanxu Yang MPH Ming Wang PhD 《Cancer》2022,128(9):1832-1839
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Pieternella C. Bots-VantSpijker Claar D. van der Maarel-Wierink Jos M.G.A. Schols Josef J.M. Bruers 《International dental journal》2022,72(2):169-178
BackgroundResearch into oral health care for older people has shown that dental care in general decreases with increasing age and frailty and, therefore, oral health care provision may be complex. The aim of this study is to identify the oral health care dentists provide to community-dwelling older people and which barriers they experience in doing this.MethodsIn this cross-sectional study, a representative sample of dentists in the Netherlands was asked to prospectively select one older patient and describe this patient using a specially developed registration form; the patient was requested to fill out a questionnaire. The relationship between experienced barriers in providing oral health care to older patients and characteristics of the dentists and the patients was studied by means univariate and multivariate logistic regression analysis.ResultsIn total, 923 dentists were asked to participate in the study. Data were available for 39.4% dentist–patient pairs. In most cases (87.4%), oral health care was focussed on conservation of the dentition. In all, 14.0% of the dentists experienced barriers in providing oral health care for older people. Some patient factors increase the risk of experiencing barriers, eg, the more difficult behaviour of older patients and the greater disease burden.ConclusionsOral health care was mostly focussed on conservation of the dentition, and dentists especially experience barriers in oral health provision to older patients if they are already frail. 相似文献
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Kawakatsu Sonoko Zhu Rui Zhang Wenhui Tang Meina T. Lu Tong Quartino Angelica L. Kågedal Matts 《Journal of pharmacokinetics and pharmacodynamics》2022,49(2):179-190
Journal of Pharmacokinetics and Pharmacodynamics - Clinical trials in patients with ulcerative colitis (UC) face the challenge of high and variable placebo response rates. The Mayo Clinical Score... 相似文献