全文获取类型
收费全文 | 201410篇 |
免费 | 2657篇 |
国内免费 | 109篇 |
专业分类
耳鼻咽喉 | 1404篇 |
儿科学 | 7351篇 |
妇产科学 | 3567篇 |
基础医学 | 20458篇 |
口腔科学 | 4034篇 |
临床医学 | 14413篇 |
内科学 | 35944篇 |
皮肤病学 | 1247篇 |
神经病学 | 18377篇 |
特种医学 | 9429篇 |
外国民族医学 | 1篇 |
外科学 | 31619篇 |
综合类 | 2651篇 |
一般理论 | 7篇 |
预防医学 | 21143篇 |
眼科学 | 3061篇 |
药学 | 11335篇 |
中国医学 | 906篇 |
肿瘤学 | 17229篇 |
出版年
2023年 | 277篇 |
2022年 | 659篇 |
2021年 | 1070篇 |
2020年 | 736篇 |
2019年 | 937篇 |
2018年 | 22834篇 |
2017年 | 18018篇 |
2016年 | 20182篇 |
2015年 | 1808篇 |
2014年 | 1972篇 |
2013年 | 2160篇 |
2012年 | 9035篇 |
2011年 | 23257篇 |
2010年 | 19976篇 |
2009年 | 12371篇 |
2008年 | 20944篇 |
2007年 | 23031篇 |
2006年 | 1829篇 |
2005年 | 3201篇 |
2004年 | 4275篇 |
2003年 | 5137篇 |
2002年 | 3195篇 |
2001年 | 800篇 |
2000年 | 997篇 |
1999年 | 631篇 |
1998年 | 363篇 |
1997年 | 312篇 |
1996年 | 199篇 |
1995年 | 204篇 |
1994年 | 182篇 |
1993年 | 128篇 |
1992年 | 249篇 |
1991年 | 286篇 |
1990年 | 315篇 |
1989年 | 263篇 |
1988年 | 226篇 |
1987年 | 169篇 |
1986年 | 141篇 |
1985年 | 149篇 |
1984年 | 119篇 |
1983年 | 102篇 |
1982年 | 65篇 |
1980年 | 73篇 |
1979年 | 85篇 |
1978年 | 83篇 |
1974年 | 81篇 |
1973年 | 63篇 |
1970年 | 79篇 |
1969年 | 67篇 |
1938年 | 60篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
Talita da Silva Mendes de Farias Ariclécio Cunha de Oliveira Sandra Andreotti Fernanda Gaspar do Amaral Patrícia Chimin André Ricardo Alves de Proença Francisco Leonardo Torres Leal Rogério Antonio Laurato Sertié Amanda Baron Campana Andressa Bolsoni Lopes Arnaldo Henrique de Souza José Cipolla‐Neto Fabio Bessa Lima 《Journal of pineal research》2015,58(3):251-261
Melatonin, the main hormone produced by the pineal gland, is secreted in a circadian manner (24‐hr period), and its oscillation influences several circadian biological rhythms, such as the regulation of clock genes expression (chronobiotic effect) and the modulation of several endocrine functions in peripheral tissues. Assuming that the circadian synchronization of clock genes can play a role in the regulation of energy metabolism and it is influenced by melatonin, our study was designed to assess possible alterations as a consequence of melatonin absence on the circadian expression of clock genes in the epididymal adipose tissue of male Wistar rats and the possible metabolic repercussions to this tissue. Our data show that pinealectomy indeed has impacts on molecular events: it abolishes the daily pattern of the expression of Clock, Per2, and Cry1 clock genes and Pparγ expression, significantly increases the amplitude of daily expression of Rev‐erbα, and affects the pattern of and impairs adipokine production, leading to a decrease in leptin levels. However, regarding some metabolic aspects of adipocyte functions, such as its ability to synthesize triacylglycerols from glucose along 24 hr, was not compromised by pinealectomy, although the daily profile of the lipogenic enzymes expression (ATP‐citrate lyase, malic enzyme, fatty acid synthase, and glucose‐6‐phosphate dehydrogenase) was abolished in pinealectomized animals. 相似文献
6.
7.
8.
Gastroesophageal reflux is the most common benign disorder of the esophagus and laparoscopic Nissen fundoplication has become the standard surgical treatment for its treatment. In our area, where the use of bougie calibration is debatable, postoperative dysphagia is encountered often after this surgery although it is usually not permanent. The aim of this study was to investigate the effect of using a soft silicone tube 39 F in diameter for esophageal calibration during laparoscopic Nissen fundoplication on the incidence of postoperative dysphagia. We divided cases scheduled to undergo laparoscopic Nissen fundoplication between January 2009 and November 2010 into two groups, each consisting 25 patients. Esophageal calibration with a 39 F silicone orogastric tube was used for the first group while there was no operative calibration in the second group. The surgical duration was recorded; the presence and severity of the postoperative dysphagia was calculated by using a dysphagia severity scoring system during the 1-year postoperative follow-up. The dysphagia severity scores were significantly lower in group 1 than group 2 on the postoperative second day and at the end of the first week and first month. We did not find a significant difference at the end of the 6-month and first year. There was also no significant difference regarding surgery duration. The use of a soft orogastric tube 39 F in diameter for esophagus calibration during laparoscopic Nissen fundoplication has significantly decreased the incidence of postoperative transient dysphagia without affecting the duration of surgery. Although dysphagia gradually resolves in the majority of patients, a safe and easy calibration method for its prevention is worth developing, and we believe that the use of our method in larger series could be beneficial. 相似文献
9.
10.