全文获取类型
收费全文 | 11250篇 |
免费 | 1706篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 204篇 |
儿科学 | 302篇 |
妇产科学 | 227篇 |
基础医学 | 1776篇 |
口腔科学 | 205篇 |
临床医学 | 1323篇 |
内科学 | 2198篇 |
皮肤病学 | 105篇 |
神经病学 | 983篇 |
特种医学 | 449篇 |
外国民族医学 | 1篇 |
外科学 | 1473篇 |
综合类 | 590篇 |
一般理论 | 8篇 |
预防医学 | 1416篇 |
眼科学 | 171篇 |
药学 | 869篇 |
中国医学 | 26篇 |
肿瘤学 | 651篇 |
出版年
2021年 | 119篇 |
2020年 | 112篇 |
2019年 | 182篇 |
2018年 | 238篇 |
2017年 | 161篇 |
2016年 | 142篇 |
2015年 | 180篇 |
2014年 | 236篇 |
2013年 | 355篇 |
2012年 | 555篇 |
2011年 | 559篇 |
2010年 | 286篇 |
2009年 | 265篇 |
2008年 | 474篇 |
2007年 | 466篇 |
2006年 | 462篇 |
2005年 | 451篇 |
2004年 | 465篇 |
2003年 | 448篇 |
2002年 | 413篇 |
2001年 | 387篇 |
2000年 | 458篇 |
1999年 | 369篇 |
1998年 | 175篇 |
1997年 | 110篇 |
1996年 | 126篇 |
1995年 | 142篇 |
1994年 | 137篇 |
1993年 | 112篇 |
1992年 | 283篇 |
1991年 | 302篇 |
1990年 | 256篇 |
1989年 | 290篇 |
1988年 | 237篇 |
1987年 | 261篇 |
1986年 | 233篇 |
1985年 | 236篇 |
1984年 | 220篇 |
1983年 | 182篇 |
1982年 | 155篇 |
1981年 | 102篇 |
1980年 | 77篇 |
1979年 | 175篇 |
1978年 | 123篇 |
1977年 | 113篇 |
1976年 | 99篇 |
1974年 | 102篇 |
1973年 | 98篇 |
1972年 | 80篇 |
1971年 | 73篇 |
排序方式: 共有10000条查询结果,搜索用时 296 毫秒
1.
2.
- The use of percutaneous mechanical support devices is becoming more embedded within the therapeutic armamentarium for patients presenting with decompensated heart failure, cardiogenic shock, and patients undergoing high risk PCI.
- The Aortix device offers a new approach to percutaneous support that appears to be safe to implement and overcomes some of the drawbacks of the extant devices.
- Further investigation remains warranted to evaluate its ultimate utility and place among the approach to the patient in need of circulatory support.
3.
4.
5.
Chancellor F. Gray Hernan A. Prieto Justin T. Deen Hari K. Parvataneni 《The Journal of arthroplasty》2019,34(2):206-210
Background
Revision total joint arthroplasty (TJA) is associated with increased readmissions, complications, and expense compared to primary TJA. Bundled payment methods have been used to improve value of care in primary TJA, but little is known of their impact in revision TJA patients. The purpose of this study is to evaluate the impact of a care redesign for a bundled payment model for primary TJA on quality metrics for revision patients, despite absence of a targeted intervention for revisions.Methods
We compared quality metrics for all revision TJA patients including readmission rate, use of post–acute care facility after discharge, length of stay, and cost, between the year leading up to the redesign and the 2 years following its implementation. Changes in the primary TJA group over the same time period were also assessed for comparison.Results
Despite a volume increase of 37% over the study period, readmissions declined from 8.9% to 5.8%. Use of post–acute care facilities decreased from 42% to 24%. Length of stay went from 4.84 to 3.92 days. Cost of the hospital episode declined by 5%.Conclusion
Our health system experienced a halo effect from our bundled payment-influenced care redesign, with revision TJA patients experiencing notable improvements in several quality metrics, though not as pronounced as in the primary TJA population. These changes benefitted the patients, the health system, and the payers. We attribute these positive changes to an altered institutional mindset, resulting from an invested and aligned care team, with active physician oversight over the care episode. 相似文献6.
Xiumei Jiang Xiaowei Zhang Patrick Gray Jiwen Zheng Timothy R. Croley Peter P. Fu 《journal of environmental science and health part c-environmental carcinogenesis & ecotoxicology reviews》2019,37(2):116-131
Gold nanoparticles (Au NPs) hold great promise in food, industrial and biomedical applications due to their unique physicochemical properties. However, influences of the gastrointestinal tract (GIT), a likely route for Au NPs administration, on the physicochemical properties of Au NPs has been rarely evaluated. Here, we investigated the influence of GIT fluids on the physicochemical properties of Au NPs (5, 50, and 100?nm) and their implications on intestinal epithelial permeability in vitro. Au NPs aggregated in fasted gastric fluids and generated hydroxyl radicals in the presence of H2O2. Cell studies showed that GIT fluids incubation of Au NPs affected the cellular uptake of Au NPs but did not induce cytotoxicity or disturb the intestinal epithelial permeability. 相似文献
7.
Bob Gray Lisa Tuckley Charlotte Cutler Simon Biddle Simon Hudson Simon Gower Lynn Vanhaecke 《Drug testing and analysis》2020,12(6):731-742
Animal sport doping control laboratories are constantly reviewing ways in which they can improve their service offering whilst ensuring that they remain economically viable. This paper describes the development and assessment of a rapid and economical method for the detection of intact glucuronide conjugates of three anabolic steroids and their metabolites along with three corticosteroids in canine urine. The analysis of intact drug conjugates for animal sport doping control is generally not performed routinely as it presents a number of analytical challenges, not least of which is the lack of availability of appropriate reference standards. Here, we report the development of a UHPLC–MS/MS method using APCI in the negative ion mode for the detection of intact phase II conjugates, including the importance of in vitro incubations in order to provide appropriate reference materials. Cross‐validation of the developed method demonstrated that the detection capability of the intact phase II conjugates of stanozolol, boldenone, nandrolone, and their metabolites along with the corticosteroids dexamethasone and methylprednisolone was equivalent to that achieved in routine race‐day screens. The new process has been in operation for approximately 2 years and has been used to analyze in excess of 13500 canine urine samples, resulting in a number of positive screening findings. To the best of our knowledge, this is the first reported use of a routine screen for intact drug conjugates within animal sport doping control. 相似文献
8.
Cui Qi N. Gray Iga N. Yu Yinxi VanderBeek Brian L. 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2019,257(9):1931-1939
Graefe's Archive for Clinical and Experimental Ophthalmology - To determine the risk of initiating ocular hypertension and glaucoma treatment with repeated injections of antivascular... 相似文献
9.
Awori Violet Nakigozi Gertrude Kisakye Alice Batte James Anok Aggrey Mayanja Richard Nakasujja Noeline Robertson Kevin R. Gray Ronald H. Wawer Maria J. Sacktor Ned Saylor Deanna 《Journal of neurovirology》2020,26(2):252-256
Journal of NeuroVirology - The Veterans Aging Cohort Study (VACS) Index has been associated with HIV-associated neurocognitive disorder (HAND) in some populations but has not been studied in... 相似文献
10.
Erin C. Tully Jackson M. Gray Sherryl H. Goodman Stephen Nowicki Jr. 《Early child development and care》2016,186(12):1939-1951
Children who expect they can bring about good outcomes and avoid bad outcomes tend to experience more personal successes. Little is known about factors that contribute to these ‘control expectancies’. The purpose of the present study was to determine whether children's internal control expectancies occur in the context of parents’ internal control expectancies, low family strain, and high family cohesiveness and whether these factors are more strongly related to daughters’ than sons’ control expectancies. A community sample of 85 children aged 9–11 years and their parents (85 mothers; 63 fathers) completed rating scales. Fathers’ more internal control expectancies and mothers’ reports of fewer family strains were associated with daughters’ but not sons’ greater internal control expectancies, and greater family cohesiveness was related to both daughters’ and sons’ internal control orientations. These findings suggest that family factors may contribute to children's, particularly daughters’, development of internal control expectancies. 相似文献