全文获取类型
收费全文 | 2485524篇 |
免费 | 187894篇 |
国内免费 | 5023篇 |
专业分类
耳鼻咽喉 | 35306篇 |
儿科学 | 83038篇 |
妇产科学 | 71777篇 |
基础医学 | 358431篇 |
口腔科学 | 69513篇 |
临床医学 | 218540篇 |
内科学 | 483816篇 |
皮肤病学 | 56286篇 |
神经病学 | 200921篇 |
特种医学 | 97830篇 |
外国民族医学 | 817篇 |
外科学 | 379268篇 |
综合类 | 54675篇 |
一般理论 | 767篇 |
预防医学 | 188531篇 |
眼科学 | 57691篇 |
药学 | 182702篇 |
2篇 | |
中国医学 | 5320篇 |
肿瘤学 | 133210篇 |
出版年
2018年 | 27007篇 |
2017年 | 20658篇 |
2016年 | 23703篇 |
2015年 | 26901篇 |
2014年 | 36843篇 |
2013年 | 55197篇 |
2012年 | 75858篇 |
2011年 | 80164篇 |
2010年 | 47394篇 |
2009年 | 44514篇 |
2008年 | 75759篇 |
2007年 | 81093篇 |
2006年 | 82079篇 |
2005年 | 80287篇 |
2004年 | 77047篇 |
2003年 | 74152篇 |
2002年 | 72363篇 |
2001年 | 116033篇 |
2000年 | 118728篇 |
1999年 | 99407篇 |
1998年 | 27156篇 |
1997年 | 24169篇 |
1996年 | 24083篇 |
1995年 | 24184篇 |
1994年 | 22325篇 |
1993年 | 20981篇 |
1992年 | 76984篇 |
1991年 | 74736篇 |
1990年 | 72838篇 |
1989年 | 70161篇 |
1988年 | 64714篇 |
1987年 | 63495篇 |
1986年 | 59893篇 |
1985年 | 57241篇 |
1984年 | 43202篇 |
1983年 | 36979篇 |
1982年 | 22305篇 |
1981年 | 19832篇 |
1979年 | 39702篇 |
1978年 | 28135篇 |
1977年 | 23737篇 |
1976年 | 22486篇 |
1975年 | 24211篇 |
1974年 | 28755篇 |
1973年 | 27696篇 |
1972年 | 26237篇 |
1971年 | 24159篇 |
1970年 | 22695篇 |
1969年 | 21496篇 |
1968年 | 20245篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Kara S. Tanaka MD Veronica R. Andaya BA Steven W. Thorpe MD Kenneth R. Gundle MD James B. Hayden MD Yee-Cheen Duong MD Raffi S. Avedian MD David G. Mohler MD Lee J. Morse MD Melissa N. Zimel MD Richard J. O'Donnell MD Andrew Fang MD Robert Lor Randall MD Tina H. Tran BS Christin New BA Rosanna L. Wustrack MD other members of Study Group FORCE 《Journal of surgical oncology》2023,127(1):148-158
2.
Post-induction hypotension is common and associated with postoperative complications. We hypothesised that pneumatic leg compression reduces post-induction hypotension in elderly patients undergoing robot-assisted laparoscopic prostatectomy. In this double-blind randomised study, patients were allocated randomly to the pneumatic leg compression group (n = 50) or control (n = 50). In the intervention group, pneumatic leg compression was initiated before induction of anaesthesia. In the control group, pneumatic leg compression was initiated 20 min after anaesthesia induction. The primary outcome was the incidence of post-induction hypotension in these groups. Post-induction hypotension was defined as systolic blood pressure < 90 mmHg during the first 20 min after induction. Haemodynamic variables and area under the curve of post-induction systolic blood pressure over time were assessed. Complications associated with pneumatic leg compression were recorded, including: peripheral neuropathy; compartment syndrome; extensive bullae beneath the leg sleeves; and pulmonary thromboembolism. The incidence of post-induction hypotension decreased in the pneumatic leg compression group compared with that in the control group; 5 (10%) vs. 29 (58%), respectively, p < 0.001. In the pneumatic leg compression group, the lowest systolic, diastolic and mean blood pressures 20 min after induction of anaesthesia were significantly greater than the control group. Pneumatic leg compression resulted in an increased area under the curve of systolic blood pressure in the first 20 min after induction, p = 0.001. There were no pneumatic leg compression-related complications. Pneumatic leg compression reduced post-induction hypotension in elderly patients undergoing robot-assisted laparoscopic prostatectomy, suggesting that it is an effective and safe intervention to prevent post-induction hypotension among elderly patients undergoing general anaesthesia. 相似文献
3.
Deitelzweig Steve Luo Xuemei Nguyen Jennifer L. Malhotra Deepa Emir Birol Russ Cristina Li Xiaoyan Lee Theodore C. Ferri Mauricio Wiederkehr Danny Reimbaeva Maya Barnes Geoffrey D. Piazza Gregory 《Journal of thrombosis and thrombolysis》2022,54(4):696-696
Journal of Thrombosis and Thrombolysis - 相似文献
4.
Jos B. Poell Leon J. Wils Arjen Brink Ralf Dietrich Christine Krieg Eunike Velleuer Ilkay Evren Elisabeth R. Brouns Jan G. de Visscher Elisabeth Bloemena Bauke Ylstra Ruud H. Brakenhoff 《International journal of cancer. Journal international du cancer》2023,152(2):227-238
Oral squamous cell carcinomas (OSCCs) develop in genetically altered epithelium in the mucosal lining, also coined as fields, which are mostly not visible but occasionally present as white oral leukoplakia (OL) lesions. We developed a noninvasive genetic assay using next-generation sequencing (NGS) on brushed cells to detect the presence of genetically altered fields, including those that are not macroscopically visible. The assay demonstrated high accuracy in OL patients when brush samples were compared with biopsies as gold standard. In a cohort of Fanconi anemia patients, detection of mutations in prospectively collected oral brushes predicted oral cancer also when visible abnormalities were absent. We further provide insight in the molecular landscape of OL with frequent changes of TP53, FAT1 and NOTCH1. NGS analysis of noninvasively collected samples offers a highly accurate method to detect genetically altered fields in the oral cavity, and predicts development of OSCC in high-risk individuals. Noninvasive genetic screening can be employed to screen high-risk populations for cancer and precancer, map the extension of OL lesions beyond what is visible, map the oral cavity for precancerous changes even when visible abnormalities are absent, test accuracy of promising imaging modalities, monitor interventions and determine genetic progression as well as the natural history of the disease in the human patient. 相似文献
5.
Jones type fifth metatarsal fractures pose a challenge to the foot and ankle surgeon, given documented high nonunion rates as well as high complication rates including hardware prominence, nerve injury, and screw breakage for existing treatment modalities including screw and plantar plate fixation. We call for the design of innovative Jones-fracture specific implants which contour to the natural curve of the fifth metatarsal. Future research should aim to expand upon existing literature for Jones fracture fixation and evaluate efficacy of novel implants which are designed to address unacceptably high complication rates for existing treatment modalities. 相似文献
6.
Ghemame M. Cathelineau C. Carsin-Nicol B. Eliat P.-A. Saint-Jalmes H. Ferré J.-C. Mouriaux F. 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2022,260(1):311-318
Graefe's Archive for Clinical and Experimental Ophthalmology - Ferromagnetic foreign bodies (FFB) present during magnetic resonance imaging (MRI) explorations can lead to tissue injury due to... 相似文献
7.
8.
9.
10.