全文获取类型
收费全文 | 617篇 |
免费 | 31篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 55篇 |
妇产科学 | 3篇 |
基础医学 | 62篇 |
口腔科学 | 13篇 |
临床医学 | 78篇 |
内科学 | 157篇 |
皮肤病学 | 21篇 |
神经病学 | 4篇 |
特种医学 | 140篇 |
外科学 | 19篇 |
综合类 | 10篇 |
预防医学 | 24篇 |
眼科学 | 4篇 |
药学 | 34篇 |
肿瘤学 | 24篇 |
出版年
2022年 | 1篇 |
2021年 | 6篇 |
2020年 | 1篇 |
2019年 | 2篇 |
2018年 | 10篇 |
2017年 | 4篇 |
2016年 | 6篇 |
2015年 | 10篇 |
2014年 | 14篇 |
2013年 | 19篇 |
2012年 | 11篇 |
2011年 | 16篇 |
2010年 | 23篇 |
2009年 | 22篇 |
2008年 | 13篇 |
2007年 | 9篇 |
2006年 | 14篇 |
2005年 | 10篇 |
2004年 | 10篇 |
2003年 | 11篇 |
2002年 | 6篇 |
2001年 | 7篇 |
2000年 | 4篇 |
1999年 | 4篇 |
1998年 | 37篇 |
1997年 | 49篇 |
1996年 | 46篇 |
1995年 | 36篇 |
1994年 | 20篇 |
1993年 | 22篇 |
1992年 | 10篇 |
1991年 | 13篇 |
1990年 | 7篇 |
1989年 | 17篇 |
1988年 | 28篇 |
1987年 | 21篇 |
1986年 | 23篇 |
1985年 | 14篇 |
1984年 | 6篇 |
1983年 | 5篇 |
1982年 | 6篇 |
1981年 | 14篇 |
1980年 | 6篇 |
1979年 | 5篇 |
1978年 | 8篇 |
1977年 | 9篇 |
1976年 | 5篇 |
1975年 | 9篇 |
1974年 | 1篇 |
排序方式: 共有650条查询结果,搜索用时 15 毫秒
1.
Anton A. Semenistyy Elena A. Litvina EA Anna G. Fedotova Chukwuweike Gwam Andrey N. Mironov 《Injury》2019,50(2):515-520
Background
Intramedullary nailing is considered a “gold standard” for treatment of tibial shaft fractures. However, some types of fractures are typically considered as “difficult for nailing”. This group includes the periarticular fractures, fractures of both bones at the same level, comminuted and segmental fractures of the tibia. Fixator-assisted nailing (FAN) is an effective method treatment of these types of fractures. The main requirements for the ideal reduction device are an ease of its installation and an ability of multiplanar fracture reduction. Fixator-assisted nailing (FAN) with the use of two perpendicular to each other monolateral tubular frames perfectly meets these requirements. In this study we present this new surgical technique and the analysis of first 30 cases.Methods
A prospective analysis was conducted for 30 patients with “difficult for nailing” tibial fractures treated with fixator-assisted nailing in our institution between September 1st, 2017, and March 1st, 2018. The duration of surgery and its different stages, the time of fluoroscopy, difficulties encountered during surgery, were analyzed. Clinical and radiological methods were used to evaluated reduction quality.Results
In all 30 cases the acceptable reduction was achieved. The mean duration of the surgical procedure was 73.7?±?3?min. The mean duration of fluoroscopy 85.9?±?4.8?s. In 7 cases we faced with technical difficulties, which were successfully addressed.Conclusion
The described technique of FAN is an effective method for the treatment of “difficult for nailing” tibial fractures. Future multi-centered studies with a larger number of patients are needed to validate our results. 相似文献2.
3.
4.
5.
6.
Systemic non‐biologic agents have long been in clinical use in medicine – often with considerable efficacy, albeit with some adverse effects – as with all medications. With the advent of biologic agents, all of which currently are restricted to systemic use, there is a growing need to ensure which agents have the better therapeutic ratio. The non‐biologic agents (NBAs) include a range of agents, most especially the corticosteroids (corticosteroids). This study reviews the corticosteroids in systemic use in management of orofacial mucocutaneous diseases; subsequent studies discuss corticosteroid‐sparing agents used in the management of orofacial diseases, such as calcineurin inhibitors used to produce immunosuppression; purine synthetase inhibitors; and cytotoxic and other immunomodulatory agents. 相似文献
7.
8.
9.
Marwa Chourabi Mei Shan Liew Shawn Lim Dorra H’mida-Ben Brahim Lobna Boussofara Liang Dai Pui Mun Wong Jia Nee Foo Badreddine Sriha Kim Samirah Robinson Simon Denil John EA Common Ons Mamaï Youcef Ben Khalifa Mathieu Bollen Jianjun Liu Mohamed Denguezli Carine Bonnard Bruno Reversade 《The Journal of investigative dermatology》2018,138(2):291-300
10.
Intravenous immune globulin and thromboembolic adverse events: A systematic review and meta‐analysis of RCTs 下载免费PDF全文
Eric M. Ammann Cole B. Haskins Kelsey M. Fillman Rebecca L. Ritter Xiaomei Gu Scott K. Winiecki Ryan M. Carnahan James C. Torner Bruce H. Fireman Michael P. Jones Elizabeth A. Chrischilles 《American journal of hematology》2016,91(6):594-605
Prior case reports and observational studies indicate that intravenous immune globulin (IVIg) products may cause thromboembolic events (TEEs), leading the FDA to require a boxed warning in 2013. The effect of IVIg treatment on the risk of serious TEEs (acute myocardial infarction, ischemic stroke, or venous thromboembolism) was assessed using adverse event data reported in randomized controlled trials (RCTs) of IVIg. RCTs of IVIg in adult patients from 1995 to 2015 were identified from Pubmed, Embase, ClinicalTrials.Gov , and two large prior reviews of IVIg's therapeutic applications. Trials at high risk of detection or reporting bias for serious adverse events were excluded. 31 RCTs with a total of 4,129 participants (2,318 IVIg‐treated, 1,811 control) were eligible for quantitative synthesis. No evidence was found of increased TEE risk among IVIg‐treated patients compared with control patients (odds ratio = 1.10, 95% CI: 0.44, 2.88; risk difference = 0.0%, 95% CI: ?0.7%, 0.7%, I2 = 0%). No significant increase in risk was found when arterial and venous TEEs were analyzed as separate endpoints. Trial publications provided little specific information concerning the methods used to ascertain potential adverse events. Care should be taken in extrapolating the results to patients with higher baseline risks of TEE. Am. J. Hematol. 91:594–605, 2016. © 2016 Wiley Periodicals, Inc. 相似文献