全文获取类型
收费全文 | 18035篇 |
免费 | 813篇 |
国内免费 | 80篇 |
专业分类
耳鼻咽喉 | 611篇 |
儿科学 | 1323篇 |
妇产科学 | 619篇 |
基础医学 | 1292篇 |
口腔科学 | 1030篇 |
临床医学 | 1364篇 |
内科学 | 3321篇 |
皮肤病学 | 456篇 |
神经病学 | 1092篇 |
特种医学 | 861篇 |
外国民族医学 | 1篇 |
外科学 | 3750篇 |
综合类 | 285篇 |
一般理论 | 8篇 |
预防医学 | 702篇 |
眼科学 | 556篇 |
药学 | 967篇 |
中国医学 | 105篇 |
肿瘤学 | 585篇 |
出版年
2023年 | 189篇 |
2022年 | 131篇 |
2021年 | 312篇 |
2020年 | 240篇 |
2019年 | 307篇 |
2018年 | 538篇 |
2017年 | 464篇 |
2016年 | 528篇 |
2015年 | 426篇 |
2014年 | 658篇 |
2013年 | 887篇 |
2012年 | 1078篇 |
2011年 | 1201篇 |
2010年 | 672篇 |
2009年 | 421篇 |
2008年 | 1009篇 |
2007年 | 1114篇 |
2006年 | 1121篇 |
2005年 | 1132篇 |
2004年 | 1055篇 |
2003年 | 991篇 |
2002年 | 1004篇 |
2001年 | 605篇 |
2000年 | 683篇 |
1999年 | 489篇 |
1998年 | 155篇 |
1997年 | 137篇 |
1996年 | 120篇 |
1995年 | 74篇 |
1994年 | 56篇 |
1993年 | 40篇 |
1992年 | 100篇 |
1991年 | 92篇 |
1990年 | 75篇 |
1989年 | 80篇 |
1988年 | 60篇 |
1987年 | 67篇 |
1986年 | 68篇 |
1985年 | 68篇 |
1984年 | 51篇 |
1983年 | 35篇 |
1982年 | 20篇 |
1979年 | 25篇 |
1975年 | 21篇 |
1974年 | 40篇 |
1973年 | 24篇 |
1971年 | 23篇 |
1970年 | 31篇 |
1969年 | 20篇 |
1967年 | 20篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Yilmaz Hülya Fırtına Sinem Sarıtaş Merve Sayitoğlu Müge Ar Muhlis Cem 《Immunologic research》2022,70(6):811-816
Immunologic Research - Hyper immunoglobulin M (HIGM) syndrome is a rare disorder of the immune system with impaired antibody functions. The clinical picture of the patients varies according to the... 相似文献
2.
Clinical Rheumatology - Aimed to evaluate the time elapsed between the onset of early symptoms and the diagnosis of fibromyalgia syndrome (FMS), the delays in diagnosis and frequent physician... 相似文献
3.
4.
Objectives
The primary objective of this study was to compare the 12-month continuation rate for women who self-injected subcutaneous depot-medroxyprogesterone acetate (DMPA-SC) with that for women receiving intramuscular depot-medroxyprogesterone acetate (DMPA-IM) from a provider. This research contributes to the broader goal of identifying solutions to support women to use contraception for their full desired duration.Study design
Participants were clients from 13 clinics in the Dakar and Thiés regions of Senegal who had decided to use injectable contraception prior to enrollment. They chose self-injection of DMPA-SC or provider administration of DMPA-IM. Self-injectors were trained and given three units of DMPA-SC. The provider-injected group received DMPA-IM and returned to the clinics for future injections. We interviewed participants at baseline and after the second, third and fourth injections (the equivalent of 12?months of contraceptive coverage). We employed Kaplan–Meier methods to estimate continuation probabilities, with a log-rank test to compare differences between groups. A multivariate Cox regression identified factors correlated with discontinuation.Results
The 12-month continuation rate for 650 women self-injecting DMPA-SC was 80.2%, while that for 649 women receiving DMPA-IM from a provider was 70.4% (p<.01). The difference in continuation between self-injectors and those receiving DMPA from a provider remained significant in a multivariate Cox regression model. The primary reason for discontinuation in both groups (44.7% self-injected; 44.5% provider-injected) was forgetting to reinject or reinjecting late. Fewer women reported side effects in the self-injection group than in the provider-administered group.Conclusions
The higher 12-month continuation rate for women self-injecting DMPA-SC relative to provider-administered DMPA-IM suggests that self-injection may help prevent pregnancy more consistently and continuously.Implications
Discontinuation of injectable contraception among women wishing to avoid pregnancy may increase unmet need in francophone West Africa. This study showed higher 12-month continuation rates for women who self-injected DMPA-SC, suggesting that this delivery method may improve injectable continuation. 相似文献5.
6.
Barbaros Erhan Çil Osman Öcal Fatma Gonca Eldem Bora Peynircioğlu Ferhun Balkancı 《Journal of vascular and interventional radiology : JVIR》2019,30(1):69-73
Purpose
To evaluate the long-term results of and patient satisfaction with trapezius ports in breast cancer patients, as an alternative to chest ports.Patients and Methods
This retrospective study included all patients who underwent trapezius port placement from December 2007 to January 2017. Seventy female patients with breast cancer, with a mean age of 54 ± 9.9 years (range, 29–76 years), were included. Indications for trapezius implantation were bilateral breast surgery or unilateral breast surgery and contralateral breast involvement. Sixty-eight of 70 patients had long-term follow-up. A retrospective, questionnaire-based survey was conducted to assess satisfaction and the trapezius port’s effect on the daily life of the patient.Results
All implantations were technically successful. Total catheter service time for 68 patients was 65,952 days (2 patients were lost to follow-up). Mean catheter service time was 969.8 days (range 7–3,458 days; median 570 days; 95% confidence interval, 739–1199; standard deviation, 947.7). No immediate procedural complications occurred. Port complications developed in 4 patients (5.9%); port infection developed in 2 patients (0.03/1,000 days); skin dehiscence developed in 1 patient (0.02/1,000 days); and port malfunction developed in 1 patient (0.02/1,000 days). The overall infection rate was 2.9% (2/68). All patients (n = 44) or a close relative (n = 17) who were interviewed with a phone call reported satisfaction regarding their ports.Conclusions
Trapezius ports offer a safe and feasible option to patients with breast cancer who need an alternative site to chest ports. It is also associated with high overall patient satisfaction. 相似文献7.
Osman Nuri Dilek Emine Özlem Gür Turan Acar Serpil Aydoğmuş 《Acta chirurgica Belgica》2019,119(4):243-247
Introduction: Endometrial cancer is the fourth most common female cancer and also distant metastases to the chest wall associated with these tumors are seen less common. Surgical treatment options for metastases of endometrial cancer are limited.Case: A 57-year-old patient who underwent total abdominal hysterectomy?+?bilateral salpingo oophorectomy and received adjuvant chemotherapy for endometrioid-type adenocarcinoma of the endometrium and tuba is presented. The patient initially presented with pleural effusion 8 years ago and the tumor was detected while during etiologic screening. The patient had no problems after adjuvant chemotherapy and had been living in another city when she presented with a mass on the chest wall measuring 20?×?15?×?12?cm 8 years after the initial diagnosis and distant organ metastasis due to the first surgery was detected. The mass was first thought to be a sarcoma and the tru-cut biopsy revealed a metastatic lesion that was immunohistochemically similar to the first surgical specimen. The mass was resected with a wide radical excision and ‘no touch’ technique. The patient was then discharged with no postoperative complications.Conclusion: Here in, a case with a distant organ metastasis due to an endometrioid-type adenocarcinoma is presented accompanied by literature data. 相似文献
8.
Nil Çomunoğlu Nuray Kepil Sergülen Dervişoğlu 《Acta orthopaedica et traumatologica turcica》2019,53(1)
Objective
The aim of this study was to define histopathological features of giant cell tumor of bone, especially accompanying fibrohistiocytic or aneurysmal bone cyst like components, in the light of our institutions experience.Methods
A total of 120 cases (64 females and 56 males; mean age: 36.2 (12–80)) with ‘GCT’ diagnosed between the years 1996–2016 were included in this retrospective analysis. Cases were evaluated according to clinical features such as age, gender, localization, recurrence, metastasis and histopathological features.Results
Tumors were localized most frequently at proximal tibia and distal femur, respectively. In 11 cases areas rich in fibrohistiocytic component and in 20 cases aneurysmal bone cyst like component were observed. In 2 cases both components were present. Twenty three cases recurred. In 1 case which was primarily located at calcaneus, tumor metastasized to lung 4 years later during follow-up.Conclusion
GCT can be confused with other tumor or tumor-like lesions involving giant cells. Secondary changes such as fibrohistiocytic or aneurysmal bone cyst-like components and coagulation necrosis were frequently seen in conventional giant cell tumor of bone. For tumors having prominent fibrohistiocytic and/or aneurysmal bone cyst-like components, in order to detect characteristic areas representing GCT, additional sampling is essential. Although secondary histopathological changes do not appear to affect clinical outcome, these features are important in differential diagnosis. Approximately one fifth of GCT cases show recurrence and sacrum and foot bones were the most frequent sites for recurrence.Level of evidence
Level IV, diagnostic study. 相似文献9.
Büşra Başar Gökcen Yasemin Akdevelioğlu Sultan Canan Nuray Bozkurt 《Gynecological endocrinology》2020,36(9):764-767
AbstractData on eating disorders in women with PCOS is insufficient. The objective of this case study was to examine the hypothesis that women with PCOS exhibit more impaired eating than healthy women. Women diagnosed with PCOS under the 2003 Rotterdam Diagnostic Criteria (n?=?40) were compared with a healthy control group (n?=?40). The groups also were divided into two as normal body weight and overweight/obese. The Eating Disorders Assessment Questionnaire (EDE-Q) and the Three Factor Eating Questionnaire (TFEQ-R21), were completed by all participants in order to evaluate eating behaviors in addition to eating disorders. Among the overweight/obese group, the average total and subscale scores of the EDE-Q as well as the total and sub-factor scores of the TFEQ-R21 were higher in women with PCOS compared to controls (p?<?.05). However, this statistically significant result was not shown among the women with normal weight (p?>?.05). In comparison to the controls, the PCOS women displayed higher values of the tool scores indicating abnormal restraint eating, body shape concern and weight concern subscale scores (p?<?.05). This result suggests that the evaluation of eating disorders should be added to routine screening and the monitoring of women with PCOS. 相似文献
10.
Ersoy Acer Hilal Kaya Erdoğan Nihan Yüksel Çanakçı Zeynep Nurhan Saracoğlu 《Cutaneous and ocular toxicology》2020,39(2)
AbstractWe read Cosansu’s commentary entitled “Effectiveness of the new inflammatory parameters in patients with chronic spontaneous urticarial” to our study with great interest. The author remarked that a limited number of patients had C-reactive protein levels and it was not specified whether there were any other drugs used by the patients and no information was given about the severity of the disease in our study. 相似文献